Literature DB >> 2224745

Foot ulceration and infections in elderly diabetics.

B A Lipsky1, R E Pecoraro, J H Ahroni.   

Abstract

Foot lesions occur commonly among patients with diabetes, particularly the elderly and those with sensory neuropathy. Because of serious or recurrent infections and impaired healing processes, initially trivial lesions may progress to chronic nonhealing wounds, gangrene, or untreatable infections that can lead to limb amputation. Strategies to prevent amputation depend on understanding the multifactorial nature of diabetic foot disease; providing effective ongoing preventive care, including patient education; and prompt and aggressive treatment of foot lesions when they occur. The approach to treatment of infections depends on many factors, including the severity of the soft tissue infection, whether or not underlying bone or joints are involved, the types of infecting organisms, the patient's social situation, and his other medical problems. Proper diagnostic studies followed by appropriate antimicrobial therapy and local wound care can usually lead to resolution of these potentially serious infections.

Entities:  

Mesh:

Year:  1990        PMID: 2224745

Source DB:  PubMed          Journal:  Clin Geriatr Med        ISSN: 0749-0690            Impact factor:   3.076


  4 in total

1.  Special considerations in the management of osteomyelitis defects (diabetes, the ischemic or dysvascular bed, and irradiation).

Authors:  Catherine M Hannan; Christopher E Attinger
Journal:  Semin Plast Surg       Date:  2009-05       Impact factor: 2.314

2.  Aerobic bacteria isolated from diabetic foot ulcers of Egyptian patients: types, antibiotic susceptibility pattern and risk factors associated with multidrug-resistant organisms.

Authors:  Mervat Mashaly; Mohamed Abo El Kheir; Mohamed Ibrahim; Wael Khafagy
Journal:  Germs       Date:  2021-12-29

3.  Hyperglycemic conditions inhibit C3-mediated immunologic control of Staphylococcus aureus.

Authors:  Pamela S Hair; Charlene G Echague; Reuben D Rohn; Neel K Krishna; Julius O Nyalwidhe; Kenji M Cunnion
Journal:  J Transl Med       Date:  2012-03-05       Impact factor: 5.531

4.  Hyperglycemia inhibits complement-mediated immunological control of S. aureus in a rat model of peritonitis.

Authors:  Clifford T Mauriello; Pamela S Hair; Reuben D Rohn; Nicholas S Rister; Neel K Krishna; Kenji M Cunnion
Journal:  J Diabetes Res       Date:  2014-12-31       Impact factor: 4.011

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.