OBJECTIVE: We conducted a cohort study to investigate whether diastolic function could predict cardiovascular (CV) events in 161 HD patients with preserved systolic function. MATERIALS AND METHODS: The ratio of early transmitral flow velocity to early mitral annular velocity (E/E') was measured by tissue Doppler imaging. Patients were stratified into two groups based on whether they experienced a CV event. RESULTS: During a 4-year follow-up period, 64 patients experienced a CV event. The E/E' values (15.18 ± 5.78) in the CV-event group were significantly higher than in the group who had not experienced a CV event (12.32 ± 4.23). Kaplan-Meier analysis indicated that the incidence of CV events was significantly higher in the group of patients whose E/E' was >15 than in the group whose E/E' was ≤ 15 (log-rank p=0.0016). Multivariate Cox proportional hazards regression analysis revealed the E/E' ratio to be a significant predictor of CV events in HD patients with preserved LV systolic function. CONCLUSION: The results of this study showed that elevated E/E' ratio in chronic HD patients predicts CV events better than other echocardiographic parameters.
OBJECTIVE: We conducted a cohort study to investigate whether diastolic function could predict cardiovascular (CV) events in 161 HDpatients with preserved systolic function. MATERIALS AND METHODS: The ratio of early transmitral flow velocity to early mitral annular velocity (E/E') was measured by tissue Doppler imaging. Patients were stratified into two groups based on whether they experienced a CV event. RESULTS: During a 4-year follow-up period, 64 patients experienced a CV event. The E/E' values (15.18 ± 5.78) in the CV-event group were significantly higher than in the group who had not experienced a CV event (12.32 ± 4.23). Kaplan-Meier analysis indicated that the incidence of CV events was significantly higher in the group of patients whose E/E' was >15 than in the group whose E/E' was ≤ 15 (log-rank p=0.0016). Multivariate Cox proportional hazards regression analysis revealed the E/E' ratio to be a significant predictor of CV events in HDpatients with preserved LV systolic function. CONCLUSION: The results of this study showed that elevated E/E' ratio in chronic HDpatients predicts CV events better than other echocardiographic parameters.
Authors: Seung Seok Han; Goo-Yeong Cho; Youn Su Park; Seon Ha Baek; Shin Young Ahn; Sejoong Kim; Ho Jun Chin; Dong-Wan Chae; Ki Young Na Journal: J Korean Med Sci Date: 2014-12-23 Impact factor: 2.153
Authors: Ruth F Dubin; Alexis L Beatty; John R Teerlink; Nelson B Schiller; Dean Alokozai; Kirsten L Johansen Journal: Echocardiography Date: 2014-11 Impact factor: 1.724
Authors: Anna Gluba-Brzózka; Marta Michalska-Kasiczak; Beata Franczyk-Skóra; Marek Nocuń; Maciej Banach; Jacek Rysz Journal: Lipids Health Dis Date: 2014-08-21 Impact factor: 3.876