Literature DB >> 22245125

Low rates of heterotopic ossification after resurfacing hip arthroplasty with use of prophylactic radiotherapy in select patients.

Tim J Kruser1, Kevin R Kozak, Donald M Cannon, Christopher S Platta, John P Heiner, Richard L Illgen.   

Abstract

Recent reports have noted higher rates of heterotopic ossification (HO) with surface replacement arthroplasty (SRA) than with traditional total hip arthroplasty in the absence of postoperative HO prophylaxis. This study reports rates and grades of HO in 44 SRA patients with at least 1 year of follow-up. Heterotopic ossification prophylaxis was used in 32 (73%) of 44 cases. Heterotopic ossification prophylaxis consisted of radiotherapy (22/32), nonsteroidal anti-inflammatory drugs (8/32), or both (2/32). One case of clinically significant HO was documented in the no-prophylaxis group. This strategy of selective HO prophylaxis in patients felt by orthopedic surgeons to be at high risk of HO resulted in low rates of clinically relevant HO after SRA (1/44, 2.3%). Further study is needed to establish optimal selection criteria for HO prophylaxis after SRA.
Copyright © 2012 Elsevier Inc. All rights reserved.

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Year:  2012        PMID: 22245125      PMCID: PMC3388168          DOI: 10.1016/j.arth.2011.11.017

Source DB:  PubMed          Journal:  J Arthroplasty        ISSN: 0883-5403            Impact factor:   4.757


  21 in total

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Journal:  J Bone Joint Surg Am       Date:  1990-02       Impact factor: 5.284

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Authors:  S Eggli; A Woo
Journal:  Arch Orthop Trauma Surg       Date:  2001-10       Impact factor: 3.067

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Authors:  C Hierton; G Blomgren; U Lindgren
Journal:  Acta Orthop Scand       Date:  1983-10

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Authors:  A F Brooker; J W Bowerman; R A Robinson; L H Riley
Journal:  J Bone Joint Surg Am       Date:  1973-12       Impact factor: 5.284

6.  Heterotopic ossification prophylaxis with indomethacin increases the risk of long-bone nonunion.

Authors:  T A Burd; M S Hughes; J O Anglen
Journal:  J Bone Joint Surg Br       Date:  2003-07

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Journal:  Radiology       Date:  1988-09       Impact factor: 11.105

Review 8.  Periarticular heterotopic ossification after total hip arthroplasty. Risk factors and consequences.

Authors:  L Ahrengart
Journal:  Clin Orthop Relat Res       Date:  1991-02       Impact factor: 4.176

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Journal:  J Bone Joint Surg Am       Date:  1981-02       Impact factor: 5.284

10.  Comparative study of the effects of radiation, indomethacin, prednisolone, and ethane-1-hydroxy-1,1-diphosphonate (EHDP) in the prevention of ectopic bone formation.

Authors:  L Ahrengart; U Lindgren; F P Reinholt
Journal:  Clin Orthop Relat Res       Date:  1988-04       Impact factor: 4.176

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  1 in total

1.  Hip resurfacing arthroplasty at a non-specialist centre.

Authors:  N K Patel; J Wright; S Sabharwal; A Afsharpad; R Bajekal
Journal:  Ann R Coll Surg Engl       Date:  2014-01       Impact factor: 1.891

  1 in total

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