Literature DB >> 22244847

Alzheimer's disease risk factor complement receptor 1 is associated with depression.

Gillian Hamilton1, Kathryn L Evans, Donald J Macintyre, Ian J Deary, Anna Dominiczak, Blair H Smith, Andrew D Morris, David J Porteous, Pippa A Thomson.   

Abstract

Variation in the complement receptor 1 gene (CR1) has been identified in recent genome-wide association studies as a risk factor for Alzheimer's disease. Here, we show that two Alzheimer's disease-associated CR1 variants, rs6656401 and rs3818361, are associated with major recurrent depression in females in a population-based cohort using individuals from the Generation Scotland: Scottish Family Health Study.
Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

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Year:  2012        PMID: 22244847     DOI: 10.1016/j.neulet.2011.12.059

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN: 0304-3940            Impact factor:   3.046


  5 in total

Review 1.  Neuroimmune nexus of depression and dementia: Shared mechanisms and therapeutic targets.

Authors:  Francis J Herman; Sherry Simkovic; Giulio M Pasinetti
Journal:  Br J Pharmacol       Date:  2019-03-21       Impact factor: 8.739

2.  Progress and Trends in Complement Therapeutics.

Authors:  Daniel Ricklin; John D Lambris
Journal:  Adv Exp Med Biol       Date:  2013       Impact factor: 2.622

3.  Assessing the presence of shared genetic architecture between Alzheimer's disease and major depressive disorder using genome-wide association data.

Authors:  J Gibson; T C Russ; M J Adams; T-K Clarke; D M Howard; L S Hall; A M Fernandez-Pujals; E M Wigmore; C Hayward; G Davies; A D Murray; B H Smith; D J Porteous; I J Deary; A M McIntosh
Journal:  Transl Psychiatry       Date:  2017-04-18       Impact factor: 6.222

Review 4.  The Impact of Disease Comorbidities in Alzheimer's Disease.

Authors:  Jose A Santiago; Judith A Potashkin
Journal:  Front Aging Neurosci       Date:  2021-02-12       Impact factor: 5.750

5.  Genome-wide screen to identify genetic loci associated with cognitive decline in late-life depression.

Authors:  D C Steffens; M E Garrett; K L Soldano; D R McQuoid; A E Ashley-Koch; G G Potter
Journal:  Int Psychogeriatr       Date:  2020-07-09       Impact factor: 3.878

  5 in total

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