Hee Kyung Yang1, Dong Sun Chungh, Jeong-Min Hwang. 1. Department of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
Abstract
PURPOSE: To determine the influence of general anesthesia and strabismus surgery on children's intellectual abilities. DESIGN: Prospective, observational study. SETTINGS: Institutional. PATIENTS: Children 5 to 10 years of age receiving general anesthesia with sevoflurane and undergoing strabismus surgery were included. Intellectual abilities were examined before and 4 weeks after surgery using the Kaufman Assessment Battery for Children. Four subtests representing intellectual abilities related to complex cortical function were examined: identification of objects in a partially completed picture, reproduction of a presented design by using rubber triangles, selecting a picture that completes or is similar to another picture, and memory for location of pictures presented on a page. MAIN OUTCOME MEASURES: Preoperative and postoperative age-adjusted scores of the 4 subtests of the Kaufman Assessment Battery for Children. RESULTS: The study group consisted of 21 children who underwent strabismus surgery under general anesthesia (mean duration, 51.3 minutes). The mean preoperative total score of the 4 subtests was 49.4±6.2. The mean postoperative total score adjusted for potential learning effects and test-retest reliability was 48.1±7.7. There was no significant postoperative change in the total score (P=.108). However, the triangle test score decreased significantly after operation (P=.019), particularly in patients with decreased stereoacuity after surgery. CONCLUSIONS: General anesthesia with sevoflurane and strabismus surgery generally do not affect the intellectual abilities of complex cortical function in children 5 to 10 years of age at 4 weeks after surgery. Cortical functions related to hand-eye coordination may be affected by transient changes in postoperative stereoacuity. Copyright Â
PURPOSE: To determine the influence of general anesthesia and strabismus surgery on children's intellectual abilities. DESIGN: Prospective, observational study. SETTINGS: Institutional. PATIENTS: Children 5 to 10 years of age receiving general anesthesia with sevoflurane and undergoing strabismus surgery were included. Intellectual abilities were examined before and 4 weeks after surgery using the Kaufman Assessment Battery for Children. Four subtests representing intellectual abilities related to complex cortical function were examined: identification of objects in a partially completed picture, reproduction of a presented design by using rubber triangles, selecting a picture that completes or is similar to another picture, and memory for location of pictures presented on a page. MAIN OUTCOME MEASURES: Preoperative and postoperative age-adjusted scores of the 4 subtests of the Kaufman Assessment Battery for Children. RESULTS: The study group consisted of 21 children who underwent strabismus surgery under general anesthesia (mean duration, 51.3 minutes). The mean preoperative total score of the 4 subtests was 49.4±6.2. The mean postoperative total score adjusted for potential learning effects and test-retest reliability was 48.1±7.7. There was no significant postoperative change in the total score (P=.108). However, the triangle test score decreased significantly after operation (P=.019), particularly in patients with decreased stereoacuity after surgery. CONCLUSIONS: General anesthesia with sevoflurane and strabismus surgery generally do not affect the intellectual abilities of complex cortical function in children 5 to 10 years of age at 4 weeks after surgery. Cortical functions related to hand-eye coordination may be affected by transient changes in postoperative stereoacuity. Copyright Â
Authors: Charles Reighard; Shaqif Junaid; William M Jackson; Ayesha Arif; Hannah Waddington; Andrew J O Whitehouse; Caleb Ing Journal: JAMA Netw Open Date: 2022-06-01
Authors: Mary W Byrne; Jeffrey A Ascherman; Pasquale Casale; Robert A Cowles; Pamela F Gallin; Lynne G Maxwell Journal: J Neurosurg Anesthesiol Date: 2012-10 Impact factor: 3.956