| Literature DB >> 22244328 |
Abstract
SIRT1 is a phylogenetically conserved energy sensor. The molecular mechanisms that regulate its catalytic activity, however, are incompletely understood. Gerhart-Hines et al. (2011) have identified β-adrenergic/cAMP signaling as a regulatory input that rapidly controls SIRT1 activity and fatty acid oxidation.Entities:
Year: 2012 PMID: 22244328 DOI: 10.1016/j.molcel.2011.12.017
Source DB: PubMed Journal: Mol Cell ISSN: 1097-2765 Impact factor: 17.970