Investigation of antibiotics in mollusks from coastal waters in the Bohai Sea of China.

This study focused on the presence and distribution of 22 antibiotics, including eight quinolones, nine sulfonamides and five macrolides in mollusks from the Bohai Sea of China. 190 samples of eleven species were collected in 2006, 2007 and 2009. Laboratory analyses revealed that antibiotics were widely distributed in the mollusks with quinolones as the major compounds with concentrations of 0.71~1575.10 μg/kg, which were up to two orders of magnitude higher than those of sulfonamides (0~76.75 μg/kg) and macrolides (0~36.21 μg/kg). The contents of quinolones and macrolides did not show significant changes from 2006, 2007 to 2009, while sulfonamides decreased significantly from 2006 to 2009. Compared with other sites, the city of Dalian was more polluted with quinolones, while Beidaihe was more contaminated with erythromycin and sulfapyridine. In addition, Mactra veneriformis and Meretrix merehjgntrix Linnaeus contained higher concentrations of quinolones and sulfamonomethoxine, while Mytilus edulis had higher levels of erythromycin and sulfapyridine.