Literature DB >> 22242289

[Comparative study between landiolol and amiodarone for therapeutic efficacy after open heart surgery].

Shunichiro Ito1, Taisuke Konishi, Tomohiro Imazuru, Kanji Matsuzaki, Tomoaki Jikuya.   

Abstract

Tachyarrhythmia, especially atrial fibrillation, remains as a common complication after open heart surgery and sometimes leads to fatal condition. Many reports showed that landiolol (ultra short-acting beta one blocker) and amiodarone were effective against postoperative atrial fibrillation (POAF). However, there were few comparative studies between these 2 drugs as prophylactic agents, and no report mentioned the therapeutic efficacy. Our study suggests that landiolol be the 1st choice for rate control of tachyarrhythmia because of easy dose adjustment and mild side effects. Amiodarone may be useful for the patients whose left ventricular function is poor.

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Year:  2011        PMID: 22242289

Source DB:  PubMed          Journal:  Kyobu Geka        ISSN: 0021-5252


  2 in total

Review 1.  Landiolol: a review of its use in intraoperative and postoperative tachyarrhythmias.

Authors:  Greg L Plosker
Journal:  Drugs       Date:  2013-06       Impact factor: 9.546

2.  Pharmacodynamic and pharmacokinetic behavior of landiolol during dobutamine challenge in healthy adults.

Authors:  Günther Krumpl; Ivan Ulč; Michaela Trebs; Pavla Kadlecová; Juri Hodisch
Journal:  BMC Pharmacol Toxicol       Date:  2020-11-25       Impact factor: 2.483

  2 in total

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