Literature DB >> 222422

ACTH-secreting carcinoma of the breast.

S D Cohle, J A Tschen, F E Smith, M Lane, M H McGavran.   

Abstract

We report a case of ACTH-secreting carcinoma of the breast. Membrane-bound secretory granules were seen within the cancer cells electron microscopically. Cytoplasmic granules reacting immunochemically to anti-ACTH antisera were seen on light microscopy. Breast cancers have been shown to secrete calcitonin, parathyroid hormone, human chorionic gonadotropin, and norepinephrine in addition to ACTH. This suggests either the presence of neuroendocrine cells in the breast as a source of such neoplasms, as in the lung, or genomic derepression during neoplastic transformation.

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Year:  1979        PMID: 222422     DOI: 10.1002/1097-0142(197906)43:6<2370::aid-cncr2820430630>3.0.co;2-x

Source DB:  PubMed          Journal:  Cancer        ISSN: 0008-543X            Impact factor:   6.860


  7 in total

1.  The significance of argyrophilia in human breast carcinomas.

Authors:  J McCutcheon; R A Walker
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1987

2.  Argyrophilic cells in carcinoma of the female breast.

Authors:  S Partanen; K Syrjänen
Journal:  Virchows Arch A Pathol Anat Histol       Date:  1981

3.  Small cell neuroendocrine (oat cell) carcinoma of the male breast. Immunocytochemical and ultrastructural investigations.

Authors:  G Jundt; A Schulz; P U Heitz; M Osborn
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1984

Review 4.  Working formulation of neuroendocrine tumors of the skin and breast.

Authors:  Sofia Asioli; Maria Pia Foschini; Riccardo Masetti; Vincenzo Eusebi
Journal:  Endocr Pathol       Date:  2014-06       Impact factor: 3.943

5.  Chromogranin A and B gene expression in carcinomas of the breast. Correlation of immunocytochemical, immunoblot, and hybridization analyses.

Authors:  A Pagani; M Papotti; H Höfler; R Weiler; H Winkler; G Bussolati
Journal:  Am J Pathol       Date:  1990-02       Impact factor: 4.307

6.  Chromogranin-reactive endocrine cells in argyrophilic carcinomas ("carcinoids") and normal tissue of the breast.

Authors:  G Bussolati; P Gugliotta; A Sapino; V Eusebi; R V Lloyd
Journal:  Am J Pathol       Date:  1985-08       Impact factor: 4.307

7.  ACTH-Producing Breast Cancer: A Patient Report.

Authors:  Naotaka Uchida; Kiyosuke Ishiguro; Takako Suda; Yasushi Horie; Motonobu Nishimura
Journal:  Yonago Acta Med       Date:  2010-12-01       Impact factor: 1.641

  7 in total

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