Literature DB >> 22242052

A female soccer player with recurrent haemoptysis and iron deficiency anaemia: idiopathic pulmonary haemosiderosis (IPH)-case report and literature review.

Roland Schroers1, Francesco Bonella, Martin Tötsch, Ulrich Costabel.   

Abstract

A 19-year-old woman presented with repeated episodes of haemoptysis and shortness of breath. Blood tests revealed iron deficiency anaemia and chest imaging studies showed bilateral lung opacities. In further laboratory tests and technical examination including bronchoalveolar lavage and transbronchial lung biopsy, pulmonary embolism, cardiac disease, and pulmonary vasculitis due to autoimmune disease were ruled out. Finally, a diagnosis of idiopathic pulmonary haemosiderosis (IPH) was made in January 2008. The patient was treated with prednisone, azathioprine, and oral iron supplementation. Subsequently, the patient's condition and haemoglobin value improved notably. In May 2009, the patient was in full disease remission including a normal blood count and normal iron parameters. IPH is a rare cause of diffuse alveolar haemorrhage of unknown origin. It occurs most frequently in children and adolescents and typically presents with recurrent haemoptysis due to alveolar bleeding. However, pulmonary signs and symptoms often are obscure in children. In these cases iron deficiency anaemia is the prominent clinical finding. The purpose of this case report is to increase awareness of IPH as a possible cause of recurrent haemoptysis and anaemia.

Entities:  

Year:  2010        PMID: 22242052      PMCID: PMC3027857          DOI: 10.1136/bcr.06.2009.1969

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  6 in total

1.  Idiopathic pulmonary hemosiderosis in an adult. Favourable response to azathioprine.

Authors:  L Airaghi; L Ciceri; S Giannini; S Ferrero; P L Meroni; A Tedeschi
Journal:  Monaldi Arch Chest Dis       Date:  2001-06

2.  Long-term clinical course of patients with idiopathic pulmonary hemosiderosis (1979-1994): prolonged survival with low-dose corticosteroid therapy.

Authors:  N Kiper; A Göçmen; U Ozçelik; E Dilber; D Anadol
Journal:  Pediatr Pulmonol       Date:  1999-03

3.  Prognosis in pediatric idiopathic pulmonary hemosiderosis.

Authors:  M M Saeed; M S Woo; E F MacLaughlin; M F Margetis; T G Keens
Journal:  Chest       Date:  1999-09       Impact factor: 9.410

Review 4.  Idiopathic pulmonary haemosiderosis. Epidemiology, pathogenic aspects and diagnosis.

Authors:  N Milman; F M Pedersen
Journal:  Respir Med       Date:  1998-07       Impact factor: 3.415

5.  [Cytologic and immunocytologic findings in bronchoalveolar lavage as a contribution to the differential diagnosis of chronic lung hemorrhage].

Authors:  R Ziesche; U Costabel; J Guzman; H Matthys
Journal:  Pneumologie       Date:  1990-02

Review 6.  Idiopathic pulmonary haemosiderosis revisited.

Authors:  O C Ioachimescu; S Sieber; A Kotch
Journal:  Eur Respir J       Date:  2004-07       Impact factor: 16.671

  6 in total
  2 in total

Review 1.  Adult patients with idiopathic pulmonary hemosiderosis: a comprehensive review of the literature.

Authors:  Biplab K Saha; Alyssa Bonnier; Santu Saha; Baidya Nath Saha; Boris Shkolnik
Journal:  Clin Rheumatol       Date:  2022-02-18       Impact factor: 3.650

Review 2.  Comparative Analysis of Adult Patients With Idiopathic Pulmonary Hemosiderosis and Lane-Hamilton Syndrome: A Systematic Review of the Literature in the Period 1971-2022.

Authors:  Biplab K Saha; Praveen Datar; Alexis Aiman; Alyssa Bonnier; Santu Saha; Nils T Milman
Journal:  Cureus       Date:  2022-03-25
  2 in total

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