Literature DB >> 22240865

Agranulocytosis induced by proton pump inhibitors.

Sandra Dury1, Julie Nardi, Claire Gozalo, François Lebargy, Gaëtan Deslee.   

Abstract

We report the first published case of agranulocytosis induced by omeprazole and its recurrence with esomeprazole, the S-isomer form of omeprazole. Interestingly, we found an homozygotous mutation of CYP2C19*17, responsible for the metabolism of proton pump inhibitors.

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Year:  2012        PMID: 22240865     DOI: 10.1097/MCG.0b013e318236f18a

Source DB:  PubMed          Journal:  J Clin Gastroenterol        ISSN: 0192-0790            Impact factor:   3.062


  2 in total

1.  Omeprazole-induced blood dyscrasia in a clozapine-treated patient.

Authors:  Robert J Philipps; Tammie Lee Demler; Claudia Lee
Journal:  Innov Clin Neurosci       Date:  2012-09

Review 2.  Advantages and Disadvantages of Long-term Proton Pump Inhibitor Use.

Authors:  Yoshikazu Kinoshita; Norihisa Ishimura; Shunji Ishihara
Journal:  J Neurogastroenterol Motil       Date:  2018-04-30       Impact factor: 4.924

  2 in total

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