Literature DB >> 22238970

[Role of selective decontamination in combined treatment of chronic anal fissure].

N M Grekova, E A Maleva, V N Bordunovskiĭ, Iu V Lebedeva.   

Abstract

Effectiveness of selective decontamination in combined treatment of patients with chronic anal fissure and concomitant proctitis was studied in clinical randomized investigation including 103 patients. The etiologically significant flora colonizing the chronic defect of the anoderma does not coincide with the composition of feces microflora and is presented by anaerobic microorganisms or a combination of aerobes and anaerobes. It was established that topical etiotropic antibacterial therapy in combination with medicamentous sphincterotomy in the outpatient treatment resulted in quicker arrest of the pain syndrome, accelerated epithelization of the fissure and made the period of treatment 2 times shorter as compared with control.

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Year:  2011        PMID: 22238970

Source DB:  PubMed          Journal:  Vestn Khir Im I I Grek        ISSN: 0042-4625


  1 in total

1.  The effects of topical application of metronidazole for treatment of chronic anal fissure: A randomized, controlled pilot study.

Authors:  Natalia Mihailovna Grekova; Elena Anatolyevna Maleva; Yuliana Lebedeva; Viktor Nicolaevich Bordunovsky; Larisa Fedorovna Telesheva; Vladimir Anatolyevich Bychkovskikh
Journal:  Indian J Gastroenterol       Date:  2015-05-01
  1 in total

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