| Literature DB >> 22236923 |
C Pierre-Audigier1, C Surcouf, V Cadet-Daniel, A Namouchi, S Heng, A Murray, B Guillard, B Gicquel.
Abstract
In a study performed in Cambodia, a higher number of tuberculosis (TB) strains with mutations in the pncA gene associated with pyrazinamide resistance (PZA-R) was found in fluoroquinolone-resistant (FQ-R) multidrug-resistant (MDR) strains (93%), compared with 47% in MDR and 3% in non-MDR strains. This emphasises the need for easy and rapid tests for identification of PZA-R for efficient treatment of MDR-TB.Entities:
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Year: 2012 PMID: 22236923 DOI: 10.5588/ijtld.11.0266
Source DB: PubMed Journal: Int J Tuberc Lung Dis ISSN: 1027-3719 Impact factor: 2.373