Literature DB >> 22236609

Leucine supplementation combined with resistance exercise improves the plasma lipid profile of dexamethasone-treated rats.

Humberto Nicastro1, Claudia R da Luz, Daniela F S Chaves, William das Neves, Kerolyn S Valente, Antonio H Lancha.   

Abstract

The impact of leucine supplementation and resistance exercise (RE) on plasma lipid profile was evaluated in adult rats treated with dexamethasone, an experimental model of dyslipidemia. Total cholesterol did not differ among groups. Furthermore, leucine supplementation did not promote improvement in the plasma total cholesterol and LDL-c of the animals. However, plasma TG and VLDL-c were significantly decreased and HDL-c increased after 7 days of leucine supplementation combined with RE. In conclusion, leucine supplementation combined with RE, but not isolated, improved the plasma lipid profile of dexamethasone-induced dyslipidemic rats.
© 2012 Nicastro et al; licensee BioMed Central Ltd.

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Year:  2012        PMID： 22236609      PMCID： PMC3268083          DOI： 10.1186/1476-511X-11-7

Source DB:  PubMed          Journal:  Lipids Health Dis        ISSN： 1476-511X            Impact factor:   3.876


  8 in total

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Authors:  Humberto Nicastro; Nelo E Zanchi; Claudia R da Luz; Wilson M A M de Moraes; Pamella Ramona; Mario A de Siqueira Filho; Daniela F S Chaves; Alessandra Medeiros; Patrícia C Brum; Dominique Dardevet; Antonio H Lancha
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  2 in total

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