| Literature DB >> 22235747 |
Mark G McLaughlin1, Matthew J Cook.
Abstract
A one-pot isomerization-Claisen protocol has been developed for the synthesis of highly substituted allylsilanes. Monosilylated divinyl ethers can be isomerized using a cationic iridium(I) catalyst followed by a thermal Claisen rearrangement to provide the allylsilanes in excellent yields and diastereoselectivities.Entities:
Year: 2012 PMID： 22235747 DOI： 10.1021/jo202560g
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354