| Literature DB >> 22235423 |
O V Potapova1, V A Shkurupiy, T V Sharkova, A V Troitskiy, N G Lusgina, A M Shestopalov.
Abstract
Oxidized dextran (60 kDa) exerted a pronounced preventive effect in laboratory mice infected with avian influenza subtype H5N1 A/Goose/Krasnoozerskoye/627/05 virus, which manifested in a significant increase in mouse lifetime (by 24.4%) and a decrease in mortality rate (3.3-fold). This was probably related to significant alleviation of pathological changes in the lungs and severity of hemodynamic and inflammatory complications and early fibrosis [corrected].Entities:
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Year: 2011 PMID： 22235423 DOI： 10.1007/s10517-011-1229-8
Source DB: PubMed Journal: Bull Exp Biol Med ISSN： 0007-4888 Impact factor: 0.804