Literature DB >> 22235402

Effects of expression of transcriptional factor AP-1 FOSL1 gene on psoriatic process.

V V Sobolev1, A D Zolotorenko, A G Soboleva, A M Elkin, S A Il'ina, D N Serov, N N Potekaev, S B Tkachenko, M T Minnibaev, A L Piruzyan.   

Abstract

We performed quantitative analysis of FOSL1 gene expression in lesional psoriatic skin. The expression of this gene in lesional psoriatic skin was significantly increased compared to that in unaffected areas. Enhanced FOSL1 expression significantly correlated with high psoriasis area and severity index (PASI). High level of FOSL1 gene expression was proposed to be a marker of pathological process activity in psoriasis.

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Year:  2011        PMID： 22235402     DOI： 10.1007/s10517-011-1208-0

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN： 0007-4888            Impact factor:   0.804


  6 in total

1.  GRHL3 binding and enhancers rearrange as epidermal keratinocytes transition between functional states.

Authors:  Rachel Herndon Klein; Ziguang Lin; Amelia Soto Hopkin; William Gordon; Lam C Tsoi; Yun Liang; Johann E Gudjonsson; Bogi Andersen
Journal:  PLoS Genet       Date:  2017-04-26       Impact factor: 5.917

Review 2.  Role of the Transcription Factor FOSL1 in Organ Development and Tumorigenesis.

Authors:  Vladimir V Sobolev; Asiat Z Khashukoeva; Olga E Evina; Natalia A Geppe; Svetlana N Chebysheva; Irina M Korsunskaya; Ekaterina Tchepourina; Alexandre Mezentsev
Journal:  Int J Mol Sci       Date:  2022-01-28       Impact factor: 5.923

Review 3.  The Fra-1: Novel role in regulating extensive immune cell states and affecting inflammatory diseases.

Authors:  Yu-Yao He; Hai-Feng Zhou; Lu Chen; Yan-Ting Wang; Wan-Li Xie; Zhen-Zhen Xu; Yue Xiong; Yi-Qi Feng; Guo-Yang Liu; Xia Li; Jie Liu; Qing-Ping Wu
Journal:  Front Immunol       Date:  2022-08-11       Impact factor: 8.786

Review 4.  Single-Cell Transcriptional Analysis Deciphers the Inflammatory Response of Skin-Resident Stromal Cells.

Authors:  Baoyi Liu; Ang Li; Jingkai Xu; Yong Cui
Journal:  Front Surg       Date:  2022-06-14

Review 5.  Roles of AIM2 Gene and AIM2 Inflammasome in the Pathogenesis and Treatment of Psoriasis.

Authors:  Jieyi Wang; Jing Gao; Cong Huang; Sohyun Jeong; Randy Ko; Xue Shen; Chaofeng Chen; Weilong Zhong; Yanfen Zou; Bo Yu; Changbing Shen
Journal:  Front Genet       Date:  2022-09-02       Impact factor: 4.772

6.  Dissecting the psoriasis transcriptome: inflammatory- and cytokine-driven gene expression in lesions from 163 patients.

Authors:  William R Swindell; Andrew Johnston; John J Voorhees; James T Elder; Johann E Gudjonsson
Journal:  BMC Genomics       Date:  2013-08-01       Impact factor: 3.969
  6 in total

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