INTRODUCTION: Catheter-associated bloodstream infection (CA-BSI) is the most common nosocomial infection in neonatal intensive care units. There is evidence that care bundles to reduce CA-BSI are effective in the adult literature. The aim of this study was to reduce CA-BSI in a Brazilian neonatal intensive care unit by means of a care bundle including few strategies or procedures of prevention and control of these infections. METHODS: An intervention designed to reduce CA-BSI with five evidence-based procedures was conducted. RESULTS: A total of sixty-seven (26.7%) CA-BSIs were observed. There were 46 (32%) episodes of culture-proven sepsis in group preintervention (24.1 per 1,000 catheter days [CVC days]). Neonates in the group after implementation of the intervention had 21 (19.6%) episodes of CA-BSI (14.9 per 1,000 CVC days). The incidence of CA-BSI decreased significantly after the intervention from the group preintervention and postintervention (32% to 19.6%, 24.1 per 1,000 CVC days to 14.9 per 1,000 CVC days, p=0.04). In the multiple logistic regression analysis, the use of more than 3 antibiotics and length of stay >8 days were independent risk factors for BSI. CONCLUSIONS: A stepwise introduction of evidence-based intervention and intensive and continuous education of all healthcare workers are effective in reducing CA-BSI.
INTRODUCTION: Catheter-associated bloodstream infection (CA-BSI) is the most common nosocomial infection in neonatal intensive care units. There is evidence that care bundles to reduce CA-BSI are effective in the adult literature. The aim of this study was to reduce CA-BSI in a Brazilian neonatal intensive care unit by means of a care bundle including few strategies or procedures of prevention and control of these infections. METHODS: An intervention designed to reduce CA-BSI with five evidence-based procedures was conducted. RESULTS: A total of sixty-seven (26.7%) CA-BSIs were observed. There were 46 (32%) episodes of culture-proven sepsis in group preintervention (24.1 per 1,000 catheter days [CVC days]). Neonates in the group after implementation of the intervention had 21 (19.6%) episodes of CA-BSI (14.9 per 1,000 CVC days). The incidence of CA-BSI decreased significantly after the intervention from the group preintervention and postintervention (32% to 19.6%, 24.1 per 1,000 CVC days to 14.9 per 1,000 CVC days, p=0.04). In the multiple logistic regression analysis, the use of more than 3 antibiotics and length of stay >8 days were independent risk factors for BSI. CONCLUSIONS: A stepwise introduction of evidence-based intervention and intensive and continuous education of all healthcare workers are effective in reducing CA-BSI.
Authors: Felicity C Fitzgerald; Walter Zingg; Gwendoline Chimhini; Simbarashe Chimhuya; Stefanie Wittmann; Helen Brotherton; Ioana D Olaru; Samuel R Neal; Neal Russell; André Ricardo Araujo da Silva; Mike Sharland; Anna C Seale; Mark F Cotton; Susan Coffin; Angela Dramowski Journal: Pediatr Infect Dis J Date: 2022-03-01 Impact factor: 2.129
Authors: Luis F Vélez; Mary Sanitato; Donna Barry; Martin Alilio; Franklin Apfel; Gloria Coe; Amparo Garcia; Michelle Kaufman; Jonathan Klein; Vesna Kutlesic; Lisa Meadowcroft; Wendy Nilsen; Gael O'Sullivan; Stefan Peterson; Daniel Raiten; Susan Vorkoper Journal: J Health Commun Date: 2014
Authors: Alexandra Molina García; James H Cross; Elizabeth J A Fitchett; Kondwani Kawaza; Uduak Okomo; Naomi E Spotswood; Msandeni Chiume; Veronica Chinyere Ezeaka; Grace Irimu; Nahya Salim; Elizabeth M Molyneux; Joy E Lawn Journal: EClinicalMedicine Date: 2022-01-10