Literature DB >> 22231238

OA in 2011: Age-related OA--a concept emerging from infancy?

Thomas Aigner1, Wiltrud Richter.   

Abstract

That primary osteoarthritis (OA) is an age-related disorder is undoubted, but how aging contributes to OA is poorly understood. New insights from 2011 offer potential explanations, novel models for study, and the suggestion that a deeper understanding of what 'aging' actually is might pave the way to everlasting joints.

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Year:  2012        PMID： 22231238     DOI： 10.1038/nrrheum.2011.206

Source DB:  PubMed          Journal:  Nat Rev Rheumatol        ISSN： 1759-4790            Impact factor:   20.543


  10 in total

1.  Growth-inhibiting conditions slow growth plate senescence.

Authors:  Patricia Forcinito; Anenisia C Andrade; Gabriela P Finkielstain; Jeffrey Baron; Ola Nilsson; Julian C Lui
Journal:  J Endocrinol       Date:  2010-10-25       Impact factor: 4.286

2.  Oxidative stress induces senescence in chondrocytes.

Authors:  Anita Brandl; Andreas Hartmann; Volker Bechmann; Bernhard Graf; Michael Nerlich; Peter Angele
Journal:  J Orthop Res       Date:  2011-01-31       Impact factor: 3.494

3.  Age-related decline in chondrocyte response to insulin-like growth factor-I: the role of growth factor binding proteins.

Authors:  J A Martin; S M Ellerbroek; J A Buckwalter
Journal:  J Orthop Res       Date:  1997-07       Impact factor: 3.494

Review 4.  Growth plate senescence and catch-up growth.

Authors:  Julian C Lui; Ola Nilsson; Jeffrey Baron
Journal:  Endocr Dev       Date:  2011-08-22

5.  Microarray analysis reveals age-related differences in gene expression during the development of osteoarthritis in mice.

Authors:  Richard F Loeser; Amy L Olex; Margaret A McNulty; Cathy S Carlson; Michael F Callahan; Cristin M Ferguson; Jeff Chou; Xiaoyan Leng; Jacquelyn S Fetrow
Journal:  Arthritis Rheum       Date:  2012-03

Review 6.  Aging theories of primary osteoarthritis: from epidemiology to molecular biology.

Authors:  T Aigner; J Rose; J Martin; J Buckwalter
Journal:  Rejuvenation Res       Date:  2004       Impact factor: 4.663

7.  Mechanisms of disease: role of chondrocytes in the pathogenesis of osteoarthritis--structure, chaos and senescence.

Authors:  Thomas Aigner; Stefan Söder; Pia M Gebhard; Audrey McAlinden; Jochen Haag
Journal:  Nat Clin Pract Rheumatol       Date:  2007-07

Review 8.  Aging and osteoarthritis: the role of chondrocyte senescence and aging changes in the cartilage matrix.

Authors:  R F Loeser
Journal:  Osteoarthritis Cartilage       Date:  2009-03-12       Impact factor: 6.576

Review 9.  Understanding the odd science of aging.

Authors:  Thomas B L Kirkwood
Journal:  Cell       Date:  2005-02-25       Impact factor: 41.582

10.  Reduced reactivation from dormancy but maintained lineage choice of human mesenchymal stem cells with donor age.

Authors:  Verena Dexheimer; Sebastian Mueller; Frank Braatz; Wiltrud Richter
Journal:  PLoS One       Date:  2011-08-05       Impact factor: 3.240
  10 in total
  10 in total

1.  Early postnatal ablation of the microRNA-processing enzyme, Drosha, causes chondrocyte death and impairs the structural integrity of the articular cartilage.

Authors:  T Kobayashi; G Papaioannou; F Mirzamohammadi; E Kozhemyakina; M Zhang; R Blelloch; M W Chong
Journal:  Osteoarthritis Cartilage       Date:  2015-02-21       Impact factor: 6.576

2.  Genome-wide mapping of DNA hydroxymethylation in osteoarthritic chondrocytes.

Authors:  Sarah E B Taylor; Ye Henry Li; Wing H Wong; Nidhi Bhutani
Journal:  Arthritis Rheumatol       Date:  2015-05       Impact factor: 10.995

3.  Involvement of ERCC1 in the pathogenesis of osteoarthritis through the modulation of apoptosis and cellular senescence.

Authors:  Koji Takayama; Yohei Kawakami; Sahnghoon Lee; Nick Greco; Mitra Lavasani; Yutaka Mifune; James H Cummins; Takashi Yurube; Ryosuke Kuroda; Masahiro Kurosaka; Freddie H Fu; Johnny Huard
Journal:  J Orthop Res       Date:  2014-06-25       Impact factor: 3.494

Review 4.  Post-traumatic osteoarthritis: from mouse models to clinical trials.

Authors:  Christopher B Little; David J Hunter
Journal:  Nat Rev Rheumatol       Date:  2013-05-21       Impact factor: 20.543

5.  H3K9ac of TGFβRI in human umbilical cord: a potential biomarker for evaluating cartilage differentiation and susceptibility to osteoarthritis via a two-step strategy.

Authors:  Yongjian Qi; Bin Li; Yinxian Wen; Xu Yang; Biao Chen; Zheng He; Zhe Zhao; Jacques Magdalou; Hui Wang; Liaobin Chen
Journal:  Stem Cell Res Ther       Date:  2021-03-04       Impact factor: 6.832

6.  Selumetinib - a potential small molecule inhibitor for osteoarthritis treatment.

Authors:  Xiaohang Zheng; Jianxin Qiu; Wenjun Pan; Yuhang Gong; Weikang Zhang; Ting Jiang; Lihua Chen; Weifu Chen; Zhenghua Hong
Journal:  Front Pharmacol       Date:  2022-09-27       Impact factor: 5.988

7.  Relationship of age and body mass index to the expression of obesity and osteoarthritis-related genes in human meniscus.

Authors:  M F Rai; L J Sandell; J M Cheverud; R H Brophy
Journal:  Int J Obes (Lond)       Date:  2013-01-15       Impact factor: 5.095

Review 8.  Nutraceuticals: potential for chondroprotection and molecular targeting of osteoarthritis.

Authors:  Daniel J Leong; Marwa Choudhury; David M Hirsh; John A Hardin; Neil J Cobelli; Hui B Sun
Journal:  Int J Mol Sci       Date:  2013-11-21       Impact factor: 5.923

9.  Prenatal caffeine exposure induces a poor quality of articular cartilage in male adult offspring rats via cholesterol accumulation in cartilage.

Authors:  Hanwen Luo; Jing Li; Hong Cao; Yang Tan; Jacques Magdalou; Liaobin Chen; Hui Wang
Journal:  Sci Rep       Date:  2015-12-07       Impact factor: 4.379

10.  Context-specific protection of TGFα null mice from osteoarthritis.

Authors:  Shirine E Usmani; Veronica Ulici; Michael A Pest; Tracy L Hill; Ian D Welch; Frank Beier
Journal:  Sci Rep       Date:  2016-07-26       Impact factor: 4.379
  10 in total

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