Literature DB >> 22230129

The mesocolon: a prospective observational study.

K Culligan1, J C Coffey, R P Kiran, M Kalady, I C Lavery, F H Remzi.   

Abstract

AIM: The aim of this study was to characterize formally the mesocolic anatomy during and following total mesocolic excision. Total mesocolic excision may improve survival in patients with colon cancer. Although this requires a detailed knowledge of normal and variant mesocolic anatomy, the latter is poorly characterized. No studies have prospectively characterized the anatomy of the entire mesocolon.
METHOD: Total mesocolic excision was performed in 109 patients undergoing total abdominal colectomy. The mesocolon was maintained intact thereby permitting a precise anatomical characterization from ileocaecal to mesorectal levels. Two- and three-dimensional schematic reconstructions were generated to illustrate in situ conformation.
RESULTS: Several previously undocumented findings emerged, including: (i) the mesocolon was continuous from ileocaecal to rectosigmoid level; (ii) a mesenteric confluence occurred at the ileocaecal and rectosigmoid junction as well as at the hepatic and splenic flexures; (iii) each flexure (and ileocaecal junction) was a complex of peritoneal and omental attachments to the colon centred on a mesenteric confluence; (iv) the proximal rectum originated at the confluence of the mesorectum and mesosigmoid; and (v) a plane occupied by Toldt's fascia separated the entire apposed mesocolon from the retroperitoneum.
CONCLUSION: When the mesocolon is fully mobilized during a total mesocolic excision of the colon, several anatomical findings that have not been previously documented emerge. These findings provide a rationalization of the surgical, embryological and anatomical approaches to the mesocolon. This has implications for all related sciences.
© 2012 The Authors. Colorectal Disease © 2012 The Association of Coloproctology of Great Britain and Ireland.

Entities:  

Mesh:

Year:  2012        PMID: 22230129     DOI: 10.1111/j.1463-1318.2012.02935.x

Source DB:  PubMed          Journal:  Colorectal Dis        ISSN: 1462-8910            Impact factor:   3.788


  32 in total

1.  Combined laparoscopic-assisted nephrectomy and complete mesocolic excision for synchronous renal and colon cancers.

Authors:  M O'Sullivan; D E Kearney; S K Giri; J C Coffey
Journal:  BMJ Case Rep       Date:  2015-09-29

2.  Anatomy of the transverse colon revisited with respect to complete mesocolic excision and possible pathways of aberrant lymphatic tumor spread.

Authors:  Sigmar Stelzner; Werner Hohenberger; Klaus Weber; Nicholas P West; Helmut Witzigmann; Thilo Wedel
Journal:  Int J Colorectal Dis       Date:  2015-11-06       Impact factor: 2.571

3.  Complete mesocolic excision and central vessel ligation for right colon cancers.

Authors:  S Killeen; H Kessler
Journal:  Tech Coloproctol       Date:  2014-10-21       Impact factor: 3.781

4.  An appraisal of the computed axial tomographic appearance of the human mesentery based on mesenteric contiguity from the duodenojejunal flexure to the mesorectal level.

Authors:  J Calvin Coffey; Kevin Culligan; Leon G Walsh; Rishab Sehgal; Colum Dunne; Deirdre McGrath; Dara Walsh; Michael Moore; Marie Staunton; Timothy Scanlon; Catherine Dewhurst; Bryan Kenny; Conor O'Riordan; Julie M O'Brien; Fabio Quondamatteo; Peter Dockery
Journal:  Eur Radiol       Date:  2015-07-18       Impact factor: 5.315

5.  A detailed appraisal of mesocolic lymphangiology--an immunohistochemical and stereological analysis.

Authors:  Kevin Culligan; Rishabh Sehgal; Daniel Mulligan; Colum Dunne; Stewart Walsh; Fabio Quondamatteo; Peter Dockery; J Calvin Coffey
Journal:  J Anat       Date:  2014-07-19       Impact factor: 2.610

Review 6.  Terminology and nomenclature in colonic surgery: universal application of a rule-based approach derived from updates on mesenteric anatomy.

Authors:  J C Coffey; R Sehgal; K Culligan; C Dunne; D McGrath; N Lawes; D Walsh
Journal:  Tech Coloproctol       Date:  2014-06-27       Impact factor: 3.781

7.  Comprehensive standardization of complete mesocolic surgery is now possible.

Authors:  R Sehgal; J C Coffey
Journal:  Tech Coloproctol       Date:  2014-03-06       Impact factor: 3.781

8.  Digital sculpting in surgery: a novel approach to depicting mesosigmoid mobilization.

Authors:  C Peirce; M Burton; I Lavery; R P Kiran; D J Walsh; P Dockery; J C Coffey
Journal:  Tech Coloproctol       Date:  2014-02-06       Impact factor: 3.781

9.  Standardization of the nomenclature based on contemporary mesocolic anatomy is paramount prior to performing a complete mesocolic excision.

Authors:  Rishabh Sehgal; J Calvin Coffey
Journal:  Int J Colorectal Dis       Date:  2014-02-02       Impact factor: 2.571

10.  An appraisal of lymph node ratio in colon and rectal cancer: not one size fits all.

Authors:  M Medani; Niall Kelly; George Samaha; G Duff; Vourneen Healy; Elizabeth Mulcahy; Eoghan Condon; David Waldron; Jean Saunders; J Calvin Coffey
Journal:  Int J Colorectal Dis       Date:  2013-05-29       Impact factor: 2.571

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