| Literature DB >> 22229863 |
Emilie Bessède1, Christiane Copie-Bergman, Philippe Lehours, Michael Levy, Karen Leroy, Maryse Baia, Audrey Riou, Francis Mégraud, Jean-Charles Delchier, Nathalie Salles.
Abstract
Abstract Helicobacter pylori infection plays a crucial role in the pathogenesis of gastric extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT). However, the host response to this infection is also important in the development of the disease. In particular, NADPH oxidases (NOXs) which generate reactive oxygen species are known to induce cell damage possibly leading to carcinogenesis. We analyze for the first time NOX expression in a series of well characterized gastric MALT lymphoma (GML) patients in comparison with controls. Our observation leads to the hypothesis that NOX2 expression is significantly associated with GML.Entities:
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Year: 2012 PMID： 22229863 PMCID： PMC3474711 DOI： 10.1089/ars.2011.4494
Source DB: PubMed Journal: Antioxid Redox Signal ISSN： 1523-0864 Impact factor: 8.401