Literature DB >> 22228578

Mutations in the sodium channel associated with pyrethroid resistance in the greenhouse whitefly, Trialeurodes vaporariorum.

Nikos Karatolos1, Kevin Gorman, Martin S Williamson, Ian Denholm.   

Abstract

BACKGROUND: Trialeurodes vaporariorum Westwood is an important pest of protected crops in temperate regions of the world. Resistance to pyrethroid insecticides is long established in this species, but the molecular basis of the mechanism(s) responsible has not previously been disclosed.
RESULTS: Mortality rates of three European strains of T. vaporariorum to the pyrethroid bifenthrin were calculated, and each possessed significant resistance (up to 662-fold) when compared with a susceptible reference strain. Direct sequencing revealed three amino acid substitutions in the para-type voltage-gated sodium channel (the pyrethroid and DDT target site) of bifenthrin-resistant T. vaporariorum at positions previously implicated with pyrethroid or DDT resistance (M918L, L925I and T929I) in other related species.
CONCLUSION: This study indicates that resistance to bifenthrin in T. vaporariorum is associated with target-site insensitivity, and that the specific mutations in the sodium channel causing resistance may differ between localities.
Copyright © 2012 Society of Chemical Industry.

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Year:  2012        PMID: 22228578     DOI: 10.1002/ps.2334

Source DB:  PubMed          Journal:  Pest Manag Sci        ISSN: 1526-498X            Impact factor:   4.845


  7 in total

1.  Diversity and Convergence of Sodium Channel Mutations Involved in Resistance to Pyrethroids.

Authors:  Frank D Rinkevich; Yuzhe Du; Ke Dong
Journal:  Pestic Biochem Physiol       Date:  2013-07-01       Impact factor: 3.963

2.  Targeting mosquito FREP1 with a fungal metabolite blocks malaria transmission.

Authors:  Guodong Niu; Bin Wang; Genwei Zhang; Jarrod B King; Robert H Cichewicz; Jun Li
Journal:  Sci Rep       Date:  2015-10-06       Impact factor: 4.379

3.  Diversity and convergence of mechanisms involved in pyrethroid resistance in the stored grain weevils, Sitophilus spp.

Authors:  Khalid Haddi; Wilson R Valbon; Luis O Viteri Jumbo; Luiz O de Oliveira; Raul N C Guedes; Eugenio E Oliveira
Journal:  Sci Rep       Date:  2018-11-05       Impact factor: 4.379

4.  Pyrethroids in an AlphaFold2 Model of the Insect Sodium Channel.

Authors:  Boris S Zhorov; Ke Dong
Journal:  Insects       Date:  2022-08-18       Impact factor: 3.139

5.  An amino acid substitution (L925V) associated with resistance to pyrethroids in Varroa destructor.

Authors:  Joel González-Cabrera; T G Emyr Davies; Linda M Field; Peter J Kennedy; Martin S Williamson
Journal:  PLoS One       Date:  2013-12-18       Impact factor: 3.240

6.  L925I mutation in the Para-type sodium channel is associated with pyrethroid resistance in Triatoma infestans from the Gran Chaco region.

Authors:  Natalia Capriotti; Gastón Mougabure-Cueto; Rolando Rivera-Pomar; Sheila Ons
Journal:  PLoS Negl Trop Dis       Date:  2014-01-23

7.  Novel Mutations in the Voltage-Gated Sodium Channel of Pyrethroid-Resistant Varroa destructor Populations from the Southeastern USA.

Authors:  Joel González-Cabrera; Sonia Rodríguez-Vargas; T G Emyr Davies; Linda M Field; Daniel Schmehl; James D Ellis; Klemens Krieger; Martin S Williamson
Journal:  PLoS One       Date:  2016-05-18       Impact factor: 3.240

  7 in total

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