BACKGROUND: Hawaii has the highest incidence of hepatocellular cancer (HCC) in the United States and the largest proportion of Asians and Pacific Islanders. HCC studies generally combine these groups into 1 ethnicity, and we sought to examine differences between Asian and Pacific Islander subpopulations. METHODS: Demographic, clinical, and treatment data for 617 patients with HCC (420 Asians, 114 whites, and 83 Pacific Islanders) were reviewed. Main outcome measures included HCC screening and liver transplantation. RESULTS: Asian and Pacific Islander subgroups had significantly more immigrants, and age was different between groups. Compared with whites, Pacific Islanders and Filipinos had less HCC screening and liver transplantation procedures, fewer met Milan criteria, and a smaller proportion of those with Milan criteria actually underwent transplantation. CONCLUSIONS: There were significant differences in risk factors, clinical presentation, treatment, and access to care among Asian, Pacific Islander, and white patients with HCC. Future HCC studies may benefit from differentiating subgroups within Asian and Pacific Islander populations to better focus these efforts.
BACKGROUND: Hawaii has the highest incidence of hepatocellular cancer (HCC) in the United States and the largest proportion of Asians and Pacific Islanders. HCC studies generally combine these groups into 1 ethnicity, and we sought to examine differences between Asian and Pacific Islander subpopulations. METHODS: Demographic, clinical, and treatment data for 617 patients with HCC (420 Asians, 114 whites, and 83 Pacific Islanders) were reviewed. Main outcome measures included HCC screening and liver transplantation. RESULTS: Asian and Pacific Islander subgroups had significantly more immigrants, and age was different between groups. Compared with whites, Pacific Islanders and Filipinos had less HCC screening and liver transplantation procedures, fewer met Milan criteria, and a smaller proportion of those with Milan criteria actually underwent transplantation. CONCLUSIONS: There were significant differences in risk factors, clinical presentation, treatment, and access to care among Asian, Pacific Islander, and white patients with HCC. Future HCC studies may benefit from differentiating subgroups within Asian and Pacific Islander populations to better focus these efforts.
Authors: Holly Hagan; Jennifer Campbell; Hanne Thiede; Steffanie Strathdee; Lawrence Ouellet; Farzana Kapadia; Sharon Hudson; Richard S Garfein Journal: Public Health Rep Date: 2006 Nov-Dec Impact factor: 2.792
Authors: Jeanette C Yu; Alfred I Neugut; Shuang Wang; Judith S Jacobson; Lauren Ferrante; Vandana Khungar; Emerson Lim; Dawn L Hershman; Robert S Brown; Abby B Siegel Journal: Cancer Date: 2010-04-01 Impact factor: 6.860
Authors: Abby B Siegel; Russell B McBride; Hashem B El-Serag; Dawn L Hershman; Robert S Brown; John F Renz; Jean Emond; Alfred I Neugut Journal: Am J Gastroenterol Date: 2007-11-15 Impact factor: 10.864
Authors: Avo Artinyan; Brian Mailey; Nicelio Sanchez-Luege; Joshua Khalili; Can-Lan Sun; Smita Bhatia; Lawrence D Wagman; Nicholas Nissen; Steven D Colquhoun; Joseph Kim Journal: Cancer Date: 2010-03-01 Impact factor: 6.860
Authors: Omar Hyder; Rebecca M Dodson; Hari Nathan; Joseph M Herman; David Cosgrove; Ihab Kamel; Jean-Francois H Geschwind; Timothy M Pawlik Journal: J Am Coll Surg Date: 2013-09-13 Impact factor: 6.113