PURPOSE: We hypothesized that the Model for End-Stage Liver Disease (MELD) score at admission to the intensive care unit (ICU) can predict in-hospital mortality for patients with liver cirrhosis. We also tested the MELD-natremia (Na) score and compared the predictive value of the 2 models. MATERIALS AND METHODS: This is a retrospective cohort study. A total of 441 consecutive patients with liver cirrhosis admitted to the ICU were included. The MELD and MELD-Na scores and other variables were obtained upon patients' admission to the ICU. RESULTS: The area under the receiver operating characteristic curve to predict in-hospital mortality was 0.77 (95% confidence interval, 0.73-0.82) for the MELD score and 0.77 (95% confidence interval, 0.73-0.81) for the MELD-Na score. CONCLUSION: The MELD scoring system provides useful prognostic information for critically ill patients with liver cirrhosis admitted to an ICU. The MELD and MELD-Na scores had similar predictive value.
PURPOSE: We hypothesized that the Model for End-Stage Liver Disease (MELD) score at admission to the intensive care unit (ICU) can predict in-hospital mortality for patients with liver cirrhosis. We also tested the MELD-natremia (Na) score and compared the predictive value of the 2 models. MATERIALS AND METHODS: This is a retrospective cohort study. A total of 441 consecutive patients with liver cirrhosis admitted to the ICU were included. The MELD and MELD-Na scores and other variables were obtained upon patients' admission to the ICU. RESULTS: The area under the receiver operating characteristic curve to predict in-hospital mortality was 0.77 (95% confidence interval, 0.73-0.82) for the MELD score and 0.77 (95% confidence interval, 0.73-0.81) for the MELD-Na score. CONCLUSION: The MELD scoring system provides useful prognostic information for critically illpatients with liver cirrhosis admitted to an ICU. The MELD and MELD-Na scores had similar predictive value.
Authors: Eric S Orman; Anthony Perkins; Marwan Ghabril; Babar A Khan; Naga Chalasani; Malaz A Boustani Journal: Metab Brain Dis Date: 2015-05-07 Impact factor: 3.584
Authors: M Dustin Boone; Leo A Celi; Ben G Ho; Michael Pencina; Michael P Curry; Yotam Lior; Daniel Talmor; Victor Novack Journal: J Crit Care Date: 2014-05-28 Impact factor: 3.425