Literature DB >> 22226828

Metabolic syndrome and mitochondrial dysfunction: insights from preclinical studies with a mitochondrially targeted antioxidant.

Tanecia Mitchell1, Victor Darley-Usmar.   

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Year:  2011        PMID： 22226828      PMCID： PMC3992111          DOI： 10.1016/j.freeradbiomed.2011.12.014

Source DB:  PubMed          Journal:  Free Radic Biol Med        ISSN： 0891-5849            Impact factor:   7.376


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  24 in total

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2.  Cardiovascular morbidity and mortality associated with the metabolic syndrome.

Authors:  B Isomaa; P Almgren; T Tuomi; B Forsén; K Lahti; M Nissén; M R Taskinen; L Groop
Journal:  Diabetes Care       Date:  2001-04       Impact factor: 19.112

3.  Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey.

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4.  The mitochondria-targeted antioxidant mitoquinone protects against cold storage injury of renal tubular cells and rat kidneys.

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5.  Obesity induces expression of uncoupling protein-2 in hepatocytes and promotes liver ATP depletion.

Authors:  K D Chavin; S Yang; H Z Lin; J Chatham; V P Chacko; J B Hoek; E Walajtys-Rode; A Rashid; C H Chen; C C Huang; T C Wu; M D Lane; A M Diehl
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6.  Hepatocyte-specific hypoxia-inducible factor-1α is a determinant of lipid accumulation and liver injury in alcohol-induced steatosis in mice.

Authors:  Bharath Nath; Ivan Levin; Timea Csak; Jan Petrasek; Christian Mueller; Karen Kodys; Donna Catalano; Pranoti Mandrekar; Gyongyi Szabo
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7.  Mitochondria-targeted antioxidant MitoQ10 improves endothelial function and attenuates cardiac hypertrophy.

Authors:  Delyth Graham; Ngan N Huynh; Carlene A Hamilton; Elisabeth Beattie; Robin A J Smith; Helena M Cochemé; Michael P Murphy; Anna F Dominiczak
Journal:  Hypertension       Date:  2009-07-06       Impact factor: 10.190

8.  Health care utilization and costs by metabolic syndrome risk factors.

Authors:  D M Boudreau; D C Malone; M A Raebel; P A Fishman; G A Nichols; A C Feldstein; A N Boscoe; R H Ben-Joseph; D J Magid; L J Okamoto
Journal:  Metab Syndr Relat Disord       Date:  2009-08       Impact factor: 1.894

9.  Mitochondria-targeted ubiquinone (MitoQ) decreases ethanol-dependent micro and macro hepatosteatosis.

Authors:  Balu K Chacko; Anup Srivastava; Michelle S Johnson; Gloria A Benavides; Mi Jung Chang; Yaozu Ye; Nirag Jhala; Michael P Murphy; Balaraman Kalyanaraman; Victor M Darley-Usmar
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10.  High fat diet induces dysregulation of hepatic oxygen gradients and mitochondrial function in vivo.

Authors:  Sudheer K Mantena; Denty Paul Vaughn; Kelly K Andringa; Heather B Eccleston; Adrienne L King; Gary A Abrams; Jeannette E Doeller; David W Kraus; Victor M Darley-Usmar; Shannon M Bailey
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Review 1.  Oncometabolites in renal cancer.

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2.  Favourable metabolic profile sustains mitophagy and prevents metabolic abnormalities in metabolically healthy obese individuals.

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Journal:  Diabetol Metab Syndr       Date:  2017-12-12       Impact factor: 3.320

3.  A SGLT2 inhibitor dapagliflozin suppresses prolonged ventricular-repolarization through augmentation of mitochondrial function in insulin-resistant metabolic syndrome rats.

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Review 4.  The Potential of the Mediterranean Diet to Improve Mitochondrial Function in Experimental Models of Obesity and Metabolic Syndrome.

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5.  Coenzyme Q10 ameliorates pain and cartilage degradation in a rat model of osteoarthritis by regulating nitric oxide and inflammatory cytokines.

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Review 6.  Oxidative stress and mitochondrial dysfunction across broad-ranging pathologies: toward mitochondria-targeted clinical strategies.

Authors:  Giovanni Pagano; Annarita Aiello Talamanca; Giuseppe Castello; Mario D Cordero; Marco d'Ischia; Maria Nicola Gadaleta; Federico V Pallardó; Sandra Petrović; Luca Tiano; Adriana Zatterale
Journal:  Oxid Med Cell Longev       Date:  2014-05-04       Impact factor: 6.543

7.  Stimulation of Alpha1-Adrenergic Receptor Ameliorates Cellular Functions of Multiorgans beyond Vasomotion through PPARδ.

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8.  Influence of Nutritional Intake of Carbohydrates on Mitochondrial Structure, Dynamics, and Functions during Adipogenesis.

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Review 9.  Pediatric Non-Alcoholic Fatty Liver Disease: Nutritional Origins and Potential Molecular Mechanisms.

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  9 in total

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