| Literature DB >> 22225635 |
Hamad M Alkahtani1, Abdullahi Y Abbas, Shudong Wang.
Abstract
We herein report the synthesis, biological activity and structure-activity relationship of derivatives of 5,6-dichloro-1-β-D-ribofuranosylbenzimidazole and benzo[d]imidazole. A lead compound 6o demonstrates potent anti-proliferative activity and the ability to induce cancer cell apoptosis.Entities:
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Year: 2011 PMID： 22225635 DOI： 10.1016/j.bmcl.2011.12.088
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823