Literature DB >> 22224260

Antifungal activity of plumericin and isoplumericin.

Dharmendra Singh1, Umakant Sharma, Parveen Kumar, Yogesh K Gupta, M P Dobhal, Sarman Singh.   

Abstract

This study evaluated the in vitro antifungal activity of the chloroform extract of Plumeria bicolor and its phytoconstituents plumericin and isoplumericin against Candida species and Cryptococcus neoformans by measuring the Minimum Inhibitory Concentration (MIC) and Minimum Fungicidal Concentration (MFC). Plumericin's consistently high activity against Candida albicans, C. krusei, C. glabrata, C. tropicalis and Cryptococcus neoformans was more potent than isoplumericin and the standard antifungal drug nystatin suggesting its potential as a drug candidate for candidiasis and cryptococcosis.

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Year:  2011        PMID： 22224260

Source DB:  PubMed          Journal:  Nat Prod Commun        ISSN： 1555-9475            Impact factor:   0.986


  5 in total

1.  Antibacterial and Antiproliferative Activities of Plumericin, an Iridoid Isolated from Momordica charantia Vine.

Authors:  Jutamas Saengsai; Sumonthip Kongtunjanphuk; Nuttawan Yoswatthana; Tanawan Kummalue; Weena Jiratchariyakul
Journal:  Evid Based Complement Alternat Med       Date:  2015-04-07       Impact factor: 2.629

2.  Antioxidant Potential of Plumieride against CCl₄-Induced Peroxidative Damage in Rats.

Authors:  Dharmendra Singh; Priya Vrat Arya; Ashutosh Sharma; Ved Prakash Aggarwal; Mahabeer Prasad Dobhal; Radhey Shyam Gupta
Journal:  Antioxidants (Basel)       Date:  2014-11-27

3.  Plumericin inhibits proliferation of vascular smooth muscle cells by blocking STAT3 signaling via S-glutathionylation.

Authors:  Elke H Heiss; Rongxia Liu; Birgit Waltenberger; Shafaat Khan; Daniel Schachner; Paul Kollmann; Kristin Zimmermann; Muris Cabaravdic; Pavel Uhrin; Hermann Stuppner; Johannes M Breuss; Atanas G Atanasov; Verena M Dirsch
Journal:  Sci Rep       Date:  2016-02-09       Impact factor: 4.379

4.  Plumericin Protects against Experimental Inflammatory Bowel Disease by Restoring Intestinal Barrier Function and Reducing Apoptosis.

Authors:  Shara Francesca Rapa; Rosanna Di Paola; Marika Cordaro; Rosalba Siracusa; Ramona D'Amico; Roberta Fusco; Giuseppina Autore; Salvatore Cuzzocrea; Hermann Stuppner; Stefania Marzocco
Journal:  Biomedicines       Date:  2021-01-12

5.  In Vitro Antiviral Activity of Potential Medicinal Plant Extracts Against Dengue and Chikungunya Viruses.

Authors:  Kalichamy Alagarasu; Poonam Patil; Meenakshi Kaushik; Deepika Chowdhury; Rajesh K Joshi; Harsha V Hegde; Mahadeo B Kakade; Sugeerappa Laxmanappa Hoti; Sarah Cherian; Deepti Parashar
Journal:  Front Cell Infect Microbiol       Date:  2022-04-07       Impact factor: 6.073
  5 in total

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