Literature DB >> 22223381

Facile synthesis, antioxidant and antimicrobial activity of amino methylene bisphosphonates.

Uma Maheswara Rao Kunda1, Satheesh Krishna Balam, Bakthavatchala Reddy Nemallapudi, Syama Sundar Chereddy, Sandip Kumar Nayak, Suresh Reddy Cirandur.   

Abstract

A green and efficient preparation method for the amino bisphosphonates is accomplished by simple mixing and stirring of diethylphosphite, triethylorthoformate and various amines in the presence of amberlyst-15 as catalyst at room temperature under solvent free conditions. The title compounds are characterized by IR, (1)H-, (13)C-, (31)P-NMR and mass spectra, also studied their antimicrobial and antioxidant activity.

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Year:  2012        PMID: 22223381     DOI: 10.1248/cpb.60.104

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN: 0009-2363            Impact factor:   1.645


  2 in total

Review 1.  Applications of alkyl orthoesters as valuable substrates in organic transformations, focusing on reaction media.

Authors:  Zahra Khademi; Kobra Nikoofar
Journal:  RSC Adv       Date:  2020-08-17       Impact factor: 4.036

2.  Microwave-assisted synthesis of (aminomethylene)bisphosphine oxides and (aminomethylene)bisphosphonates by a three-component condensation.

Authors:  Erika Bálint; Ádám Tajti; Anna Dzielak; Gerhard Hägele; György Keglevich
Journal:  Beilstein J Org Chem       Date:  2016-07-19       Impact factor: 2.883

  2 in total

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