Literature DB >> 22223262

Combinatorial chemistry has matured in the last three decades: dedicated to Professor Árpád Furka on the occasion of his 80th birthday.

Gábor Dibó1.   

Abstract

Combinatorial chemistry was introduced in the 1980s. It provided the possibility to produce new compounds in practically unlimited number. New strategies and technologies have also been developed that made it possible to screen very large number of compounds and to identify useful components in mixtures containing millions of different substances. This dramatically changed the drug discovery process and the way of thinking of synthetic chemists. In addition, combinatorial strategies became useful in areas such as pharmaceutical research, agrochemistry, catalyst design, and materials research. Prof. Árpád Furka is one of the pioneers of combinatorial chemistry.

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Year:  2012        PMID: 22223262     DOI: 10.1007/s11030-011-9351-0

Source DB:  PubMed          Journal:  Mol Divers        ISSN: 1381-1991            Impact factor:   2.943


  7 in total

1.  String synthesis. A spatially addressable split procedure

Authors: 
Journal:  J Comb Chem       Date:  2000-05

2.  Rapid solid-phase peptide synthesis using thermal and controlled microwave irradiation.

Authors:  Bernadett Bacsa; Bimbisar Desai; Gábor Dibó; C Oliver Kappe
Journal:  J Pept Sci       Date:  2006-10       Impact factor: 1.905

3.  Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery.

Authors:  R A Houghten; C Pinilla; S E Blondelle; J R Appel; C T Dooley; J H Cuervo
Journal:  Nature       Date:  1991-11-07       Impact factor: 49.962

4.  A multidimensional overpressured layer chromatographic method for the characterization of tetrazine libraries.

Authors:  Naran Gombosuren; Zoltán Novák; András Kotschy; Emil Mincsovics; Gábor Dibó
Journal:  J Biochem Biophys Methods       Date:  2006-01-24

5.  Preparation of cherry-picked combinatorial libraries by string synthesis.

Authors:  Arpád Furka; Gábor Dibó; Naran Gombosuren
Journal:  Curr Drug Discov Technol       Date:  2005-03

6.  A new type of synthetic peptide library for identifying ligand-binding activity.

Authors:  K S Lam; S E Salmon; E M Hersh; V J Hruby; W M Kazmierski; R J Knapp
Journal:  Nature       Date:  1991-11-07       Impact factor: 49.962

7.  General method for rapid synthesis of multicomponent peptide mixtures.

Authors:  A Furka; F Sebestyén; M Asgedom; G Dibó
Journal:  Int J Pept Protein Res       Date:  1991-06
  7 in total

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