Literature DB >> 22221154

Efficacy of uterine artery embolisation for treatment of symptomatic fibroids and adenomyosis - an interim report on an Australian experience.

Eisen Liang1, Bevan Brown, Rodney Kirsop, Paul Stewart, Andrew Stuart.   

Abstract

BACKGROUND: Uterine artery embolisation (UAE) has been widely described internationally, however there is a paucity of data reported from Australia. AIM: To conduct a local audit on the efficacy and safety of UAE treating symptomatic fibroids and adenomyosis.
METHODS: Clinical data of 76 consecutive UAEs were reviewed. Degree of fibroid-related symptoms before embolisation and at follow-up visits were compared. Procedural and subsequent complications were recorded. Uterine and fibroid volumes were measured on MRI at baseline and six months post-UAE.
RESULTS: Seventy-six UAEs were performed in 75 women. Fifty-nine women had follow-up duration of more than six months, and one woman was lost to follow-up. Clinical success was 93% overall (n = 59) and 96% for menorrhagia (n = 49). For dysmenorrhoea (n = 36), 89% of women had at least some improvement, 75% had significant improvement and 56% had resolution of pain. For urinary symptoms (n = 32), 97% of women had at least some improvement and 50% had resolution of all urinary symptoms. Adenomyosis was found in 17 (29%) women treated. The primary success rate was 96%, and secondary success rate (after repeat UAE) was 100%. MRI showed 50% uterine volume reduction and 60% dominant fibroid volume reduction. There were no significant procedural-related acute complications. There were three possible cases of endometritis, two managed conservatively and one required hysterectomy.
CONCLUSIONS: This audit, based on local Australian experience, has confirmed that UAE is a safe and highly effective treatment for women with symptomatic fibroids and/or adenomyosis.
© 2012 The Authors Australian and New Zealand Journal of Obstetrics and Gynaecology © 2012 The Royal Australian and New Zealand College of Obstetricians and Gynaecologists.

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Mesh:

Year:  2012        PMID: 22221154     DOI: 10.1111/j.1479-828X.2011.01399.x

Source DB:  PubMed          Journal:  Aust N Z J Obstet Gynaecol        ISSN: 0004-8666            Impact factor:   2.100


  6 in total

1.  Adenomyosis: Epidemiology, Risk Factors, Clinical Phenotype and Surgical and Interventional Alternatives to Hysterectomy.

Authors:  F A Taran; E A Stewart; S Brucker
Journal:  Geburtshilfe Frauenheilkd       Date:  2013-09       Impact factor: 2.915

Review 2.  Clinical and periprocedural pain management for uterine artery embolization.

Authors:  Elizabeth Brooke Spencer; Peter Stratil; Heidi Mizones
Journal:  Semin Intervent Radiol       Date:  2013-12       Impact factor: 1.513

3.  Effects of the intermittent injection with super-low pressure on the postoperative pain control during the uterine artery embolization for uterine myoma.

Authors:  Jian-Bo Zhao; Ze-Long Luo; Chao Feng; Qing-Le Zeng; Xiao-Feng He; Yan-Hao Li; Yong Chen
Journal:  Int J Clin Exp Med       Date:  2015-08-15

4.  Outcomes in Adenomyosis Treated with Uterine Artery Embolization Are Associated with Lesion Vascularity: A Long-Term Follow-Up Study of 252 Cases.

Authors:  Jing Zhou; Li He; Ping Liu; Hui Duan; Hanze Zhang; Weili Li; Shipeng Gong; Guidong Su; Chunlin Chen
Journal:  PLoS One       Date:  2016-11-02       Impact factor: 3.240

5.  Uterine Artery Embolization Versus Hysterectomy in the Treatment of Symptomatic Adenomyosis: Protocol for the Randomized QUESTA Trial.

Authors:  Annefleur Machteld de Bruijn; Wouter Jk Hehenkamp; Paul Nm Lohle; Judith Af Huirne; Jolanda de Vries; Moniek Twisk
Journal:  JMIR Res Protoc       Date:  2018-03-01

6.  Changes in Hysterectomy Route and Adnexal Removal for Benign Disease in Australia 2001-2015: A National Population-Based Study.

Authors:  Natalie De Cure; Stephen J Robson
Journal:  Minim Invasive Surg       Date:  2018-05-31
  6 in total

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