Literature DB >> 22220480

Irreversible inhibitors of tissue transglutaminase.

Jeffrey W Keillor1, Nicolas Chabot, Isabelle Roy, Amina Mulani, Olivier Leogane, Christophe Pardin.   

Abstract

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Year:  2011        PMID： 22220480     DOI： 10.1002/9781118105771.ch10

Source DB:  PubMed          Journal:  Adv Enzymol Relat Areas Mol Biol        ISSN： 0065-258X


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  6 in total

1.  Irreversible 4-Aminopiperidine Transglutaminase 2 Inhibitors for Huntington's Disease.

Authors:  Michael E Prime; Frederick A Brookfield; Stephen M Courtney; Simon Gaines; Richard W Marston; Osamu Ichihara; Marie Li; Darshan Vaidya; Helen Williams; Anna Pedret-Dunn; Laura Reed; Sabine Schaertl; Leticia Toledo-Sherman; Maria Beconi; Douglas Macdonald; Ignacio Muñoz-Sanjuan; Celia Dominguez; John Wityak
Journal:  ACS Med Chem Lett       Date:  2012-08-09       Impact factor: 4.345

2.  SAR Development of Lysine-Based Irreversible Inhibitors of Transglutaminase 2 for Huntington's Disease.

Authors:  John Wityak; Michael E Prime; Frederick A Brookfield; Stephen M Courtney; Sayeh Erfan; Siw Johnsen; Peter D Johnson; Marie Li; Richard W Marston; Laura Reed; Darshan Vaidya; Sabine Schaertl; Anna Pedret-Dunn; Maria Beconi; Douglas Macdonald; Ignacio Muñoz-Sanjuan; Celia Dominguez
Journal:  ACS Med Chem Lett       Date:  2012-10-04       Impact factor: 4.345

3.  Sulforaphane covalently interacts with the transglutaminase 2 cancer maintenance protein to alter its structure and suppress its activity.

Authors:  Ellen A Rorke; Gautam Adhikary; Henryk Szmacinski; Joseph R Lakowicz; David J Weber; Raquel Godoy-Ruiz; Purushottamachar Puranik; Jeffrey W Keillor; Eric W J Gates; Richard L Eckert
Journal:  Mol Carcinog       Date:  2021-10-05       Impact factor: 4.784

4.  Structure-Activity Relationships of Potent, Targeted Covalent Inhibitors That Abolish Both the Transamidation and GTP Binding Activities of Human Tissue Transglutaminase.

Authors:  Abdullah Akbar; Nicole M R McNeil; Marie R Albert; Viviane Ta; Gautam Adhikary; Karine Bourgeois; Richard L Eckert; Jeffrey W Keillor
Journal:  J Med Chem       Date:  2017-09-14       Impact factor: 7.446

5.  Dihydroisoxazole inhibitors of Anopheles gambiae seminal transglutaminase AgTG3.

Authors:  Binh V Le; Cornelius Klöck; Alexandra Schatz; Jennifer B Nguyen; Evdoxia G Kakani; Flaminia Catteruccia; Chaitan Khosla; Richard H G Baxter
Journal:  Malar J       Date:  2014-06-02       Impact factor: 2.979

6.  Transamidase site-targeted agents alter the conformation of the transglutaminase cancer stem cell survival protein to reduce GTP binding activity and cancer stem cell survival.

Authors:  C Kerr; H Szmacinski; M L Fisher; B Nance; J R Lakowicz; A Akbar; J W Keillor; T Lok Wong; R Godoy-Ruiz; E A Toth; D J Weber; R L Eckert
Journal:  Oncogene       Date:  2016-12-12       Impact factor: 9.867
  6 in total

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