UNLABELLED: The HAM/TSP caused by HTLV-1 infection usually affects patients to disabling states, and sometimes can lead them to paraplegia presenting symptoms of depression and anxiety, impacting on quality of life. OBJECTIVE: The purpose of this study was to evaluate the frequency of depression and anxiety and its impact on quality of life in HTLV-1-infected TSP/HAM patients. MATERIAL AND METHODS: This was a cross-sectional study including 67 asymptomatic (control group) and 63 with TSP/HAM subjects. The instruments used were a demographic questionnaire, scales for anxiety and depression diagnosis (BDI and BAI), questionnaire for the assessment of Quality of Life of the World Health Organization (WHOQOL-Brief) and neurological scale to measure the disability level (Osame's Disability Status Scale). All patients had HTLV-I diagnosis by serological and molecular approaches, monitored at Instituto de Infectologia Emílio Ribas from May 2008 to July 2009. Data were analyzed statistically by frequencies, the Mann-Whitney test and the Spearman correlation test. Data among groups were analyzed and correlated with functional and severity aspects. RESULTS: The results showed that patients with HAM/TSP compared to asymptomatic carriers had higher rates of depression (p < 0.001) and anxiety (p < 0.001), and impairment on quality of life in the areas of: dissatisfaction with health (p < 0.001), physical (p < 0.001) and the environment (p = 0.003). The main factors that correlated with levels of depression and anxiety and the domains of the WHOQOL-brief were: education, family income and social class. CONCLUSION: A well conducted evaluation and counseling may help in treatment, for a better quality of life of these patients.
UNLABELLED: The HAM/TSP caused by HTLV-1 infection usually affects patients to disabling states, and sometimes can lead them to paraplegia presenting symptoms of depression and anxiety, impacting on quality of life. OBJECTIVE: The purpose of this study was to evaluate the frequency of depression and anxiety and its impact on quality of life in HTLV-1-infected TSP/HAMpatients. MATERIAL AND METHODS: This was a cross-sectional study including 67 asymptomatic (control group) and 63 with TSP/HAM subjects. The instruments used were a demographic questionnaire, scales for anxiety and depression diagnosis (BDI and BAI), questionnaire for the assessment of Quality of Life of the World Health Organization (WHOQOL-Brief) and neurological scale to measure the disability level (Osame's Disability Status Scale). All patients had HTLV-I diagnosis by serological and molecular approaches, monitored at Instituto de Infectologia Emílio Ribas from May 2008 to July 2009. Data were analyzed statistically by frequencies, the Mann-Whitney test and the Spearman correlation test. Data among groups were analyzed and correlated with functional and severity aspects. RESULTS: The results showed that patients with HAM/TSP compared to asymptomatic carriers had higher rates of depression (p < 0.001) and anxiety (p < 0.001), and impairment on quality of life in the areas of: dissatisfaction with health (p < 0.001), physical (p < 0.001) and the environment (p = 0.003). The main factors that correlated with levels of depression and anxiety and the domains of the WHOQOL-brief were: education, family income and social class. CONCLUSION: A well conducted evaluation and counseling may help in treatment, for a better quality of life of these patients.
Authors: Glória O Orge; Thais R Dellavechia; José Abraão Carneiro-Neto; Lucas Araújo-de-Freitas; Carla H C Daltro; Carlos T Santos; Lucas C Quarantini Journal: PLoS One Date: 2015-05-27 Impact factor: 3.240
Authors: Katia N Sá; Maíra C Macêdo; Rosana P Andrade; Selena D Mendes; José V Martins; Abrahão F Baptista Journal: J Multidiscip Healthc Date: 2015-02-23
Authors: Carolina Rosadas; Tatiane Assone; Marina Yamashita; Adine Adonis; Marzia Puccioni-Sohler; Marisa Santos; Arthur Paiva; Jorge Casseb; Augusto C P Oliveira; Graham P Taylor Journal: PLoS Negl Trop Dis Date: 2020-10-16
Authors: Maria Rita Polo Gascón; Claudio Garcia Capitão; Maria Cezira Fantini Nogueira-Martins; Jorge Casseb; Augusto Cesar Penalva Oliveira Journal: ISRN Psychiatry Date: 2012-07-01