| Literature DB >> 22218458 |
Agustín Díaz1, Vipin Saxena, Julissa González, Amanda David, Barbara Casañas, Carrie Carpenter, James D Batteas, Jorge L Colón, Abraham Clearfield, M Delwar Hussain.
Abstract
Doxorubicin was intercalated into novel zirconium phosphate nano-platelets (ZrP). The obtained doxorubicin intercalated ZrP nano-platelets had an impressive 34.9% (w/w) drug loading. We used this material to deliver doxorubicin to breast cancer cells (MCF-7). Cellular studies with MCF-7 cells showed higher uptake and cytotoxicity of doxorubicin loaded ZrP compared to free doxorubicin. This journal is © The Royal Society of Chemistry 2012Entities:
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Year: 2012 PMID: 22218458 DOI: 10.1039/c2cc16218k
Source DB: PubMed Journal: Chem Commun (Camb) ISSN: 1359-7345 Impact factor: 6.222