| Literature DB >> 22218439 |
Durval Damiani1, Valesca Mansur Kuba, Louise Cominato, Daniel Damiani, Vaê Dichtchekenian, Hamilton Cabral de Menezes Filho.
Abstract
Metabolic syndrome (MS) has been a condition involved in considerable controversy, starting with the terminology. Gerald Reaven himself, the author who proposed the term MS, advised against the use of this terminology because the definition implies in at least three metabolic alterations, and it is never clear to which group of alterations we are referring to when we say that a patient has MS. In children, the problem is even more complicated, since there are many different adaptations to the criteria used in adults. On the other hand, independent of the terminology, cardiovascular risks are well-established and it is very clear that even children may present metabolic disturbances which predict future metabolic problems. The role of the pediatric endocrinologist or the general pediatrician is to investigate, especially in overweight/obese children, conditions that if treated early, may prevent future complications that today, unfortunately, are being diagnosed only in adult life. In this review, we discuss problems on the definition, epidemiology, pathophysiology, and complications of MS in children and adolescents.Entities:
Mesh:
Year: 2011 PMID: 22218439 DOI: 10.1590/s0004-27302011000800011
Source DB: PubMed Journal: Arq Bras Endocrinol Metabol ISSN: 0004-2730