Re2O(7)-catalyzed three-component synthesis of protected secondary and tertiary homoallylic amines.

Three-component synthesis of protected secondary and "for the first time" tertiary homoallylic amines is achieved from carbonyl, carbamate, and allyltrimethylsilanes using a Re(2)O(7)-catalyst under mild and open flask conditions. Excellent chemoselectivities and diastereoselectivities were observed. This journal is © The Royal Society of Chemistry 2012