OBJECTIVE: To evaluate the efficacy of surgical therapy for carotid body tumors. METHODS: A retrospective analysis was conducted, covering the diagnosis, surgical procedure, postoperative complications, and prognosis of 120 cases of carotid body tumors in Peking Union Medical College Hospital from 1949 to May, 2011. RESULTS: Surgical excision was successfully performed in 111 cases with 117 tumors. In all those cases, 50 underwent simple tumor resection, 42 underwent resection of tumors and ligation of the external carotid arteries, 7 underwent co-resection of tumors and common carotid arteries, internal carotid arteries, as well as external arteries without vascular reconstruction, and the other 12 cases experienced tumor resection and vascular reconstruction as internal carotid arteries were involved. After operation, 3 cases developed cerebral infarction, 30 cases showed cranial nerve palsy, including 15 cases of hypoglossal nerve damage, 10 cases of vagus paralysis, and 5 cases of Horner's syndrome. CONCLUSION: It is essential to make a proper surgical strategy, which can reduce postoperative complications.
OBJECTIVE: To evaluate the efficacy of surgical therapy for carotid body tumors. METHODS: A retrospective analysis was conducted, covering the diagnosis, surgical procedure, postoperative complications, and prognosis of 120 cases of carotid body tumors in Peking Union Medical College Hospital from 1949 to May, 2011. RESULTS: Surgical excision was successfully performed in 111 cases with 117 tumors. In all those cases, 50 underwent simple tumor resection, 42 underwent resection of tumors and ligation of the external carotid arteries, 7 underwent co-resection of tumors and common carotid arteries, internal carotid arteries, as well as external arteries without vascular reconstruction, and the other 12 cases experienced tumor resection and vascular reconstruction as internal carotid arteries were involved. After operation, 3 cases developed cerebral infarction, 30 cases showed cranial nerve palsy, including 15 cases of hypoglossal nerve damage, 10 cases of vagus paralysis, and 5 cases of Horner's syndrome. CONCLUSION: It is essential to make a proper surgical strategy, which can reduce postoperative complications.
Authors: Leonie T van Hulsteijn; Berdine Heesterman; Jeroen C Jansen; Jean-Pierre Bayley; Frederik J Hes; Eleonora P M Corssmit; Olaf M Dekkers Journal: Eur J Hum Genet Date: 2015-03-11 Impact factor: 4.246