Literature DB >> 22216500

Effects of oral salbutamol and pirbuterol on FEV1, heart rate and blood pressure in asthmatics.

R F Willey1, I W Grant, S J Pocock.   

Abstract

In a double-blind trial the effects on ventilatory function (FEV1), heart rate and blood pressure of oral pirbuterol and oral salbutamol in various single doses were studied in ten patients with chronic asthma. Pirbuterol (15 mg) and salbutamol (4 mg) produced equal peak levels of bronchodilatation. There was no significant difference in the mean rise in heart rates caused by the two drugs, and no other significant side-effects were noted.

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Year:  1976        PMID: 22216500      PMCID: PMC1428897          DOI: 10.1111/j.1365-2125.1976.tb04881.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN: 0306-5251            Impact factor:   4.335


  4 in total

1.  SC-10049: a catecholamine bronchodilator and hyperglycemic agent.

Authors:  C G VAN ARMAN; L M MILLER; M P O'MALLEY
Journal:  J Pharmacol Exp Ther       Date:  1961-07       Impact factor: 4.030

2.  Pyrbuterol: a new bronchodilator. Phase I-single dose study.

Authors:  S N Steen; I Ziment; J S Thomas
Journal:  Curr Ther Res Clin Exp       Date:  1974-10

3.  Comparison of two oral selective beta2-adrenergic stimulant drugs in bronchial asthma.

Authors:  J S Legge; J Gaddie; K N Palmer
Journal:  Br Med J       Date:  1971-03-20

4.  Bronchodilator effect of oral salbutamol in asthmatics treated with corticosteroids.

Authors:  S S Parker; Y F Choo-Kang; E J Cooper; S J Cameron; I W Grant
Journal:  Br Med J       Date:  1971-10-16
  4 in total
  2 in total

1.  Comparison of pirbuterol and pirbuterol and hydroxyzine in patients with reversible airway obstruction.

Authors:  H Poppius; H Lehti; B Stenius-Aarniala
Journal:  Eur J Clin Pharmacol       Date:  1979-07       Impact factor: 2.953

Review 2.  Pirbuterol. A preliminary review of its pharmacological properties and therapeutic efficacy in reversible bronchospastic disease.

Authors:  D M Richards; R N Brogden
Journal:  Drugs       Date:  1985-07       Impact factor: 9.546

  2 in total

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