Literature DB >> 22215142

Successful treatment of severe disruptive disorder featuring symptoms of the Klüver-Bucy Syndrome following a massive right temporal-parietal hemorrhage.

Luigi De Benedictis, Alexandre Dumais, Pierre Landry.   

Abstract

We know little about effective treatment for patients suffering from partial or complete Klüver-Bucy Syndrome (KBS) and other disruptive behaviors following a stroke. Reported cases have shown that certain medication, given alone or combined, can be partially effective. In this specific case study, we will try to demonstrate the effectiveness of a combination of carbamazepine, clonidine, quetiapine and methylphenidate in the alleviating of these symptoms. The wide range of symptoms found in KBS led us to use several kinds of psychotropic medication in spite of the inherent risks associated to polypharmacy.

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Year:  2012        PMID: 22215142     DOI: 10.1007/s10072-011-0911-y

Source DB:  PubMed          Journal:  Neurol Sci        ISSN: 1590-1874            Impact factor:   3.307


  7 in total

1.  Carbamazepine in agitation and aggressive behaviour following severe closed-head injury: results of an open trial.

Authors:  P Azouvi; C Jokic; N Attal; P Denys; S Markabi; B Bussel
Journal:  Brain Inj       Date:  1999-10       Impact factor: 2.311

2.  A pilot study of quetiapine treatment of aggression due to traumatic brain injury.

Authors:  Edward Kim; Mona Bijlani
Journal:  J Neuropsychiatry Clin Neurosci       Date:  2006       Impact factor: 2.198

Review 3.  Use of methylphenidate in traumatic brain injury.

Authors:  O'Rita M Siddall
Journal:  Ann Pharmacother       Date:  2005-05-24       Impact factor: 3.154

4.  Hyperorality in epileptic seizures: periictal incomplete Klüver-Bucy syndrome.

Authors:  Jozsef Janszky; Andras Fogarasi; Vafa Magalova; Ingrid Tuxhorn; Alois Ebner
Journal:  Epilepsia       Date:  2005-08       Impact factor: 5.864

5.  Selective serotonin reuptake inhibitor treatment of post-traumatic Klüver-Bucy syndrome.

Authors:  J Slaughter; W Bobo; M K Childers
Journal:  Brain Inj       Date:  1999-01       Impact factor: 2.311

6.  Classification and regression trees (CART) for prediction of function at 1 year following head trauma.

Authors:  N R Temkin; R Holubkov; J E Machamer; H R Winn; S S Dikmen
Journal:  J Neurosurg       Date:  1995-05       Impact factor: 5.115

7.  Contrasting effects of clonidine and diazepam on tests of working memory and planning.

Authors:  J T Coull; H C Middleton; T W Robbins; B J Sahakian
Journal:  Psychopharmacology (Berl)       Date:  1995-08       Impact factor: 4.530

  7 in total

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