Literature DB >> 2221504

Implants, transplants, and other parts of the medicine of the future.

C A Roth1, C Lenfant.   

Abstract

Today, therapies that rely on adding something "more than natural" to the patient are a commonplace of medical practice. Although we may view such therapies as recent developments of biomedical science and engineering, they are actually the culmination of efforts to replicate, replace, and enhance parts of the human anatomy that date from the early days of recorded history. A review of some of those early efforts is an instructive way to begin. It helps us to appreciate that current developments at the forefront of biomedical science and engineering will soon transform the implants and transplants of today into the relatively primitive implants and transplants of the past. A discussion of the present state of implants and transplants follows. It is necessary to allow us to appreciate the great potential offered by current biomedical science and engineering for future developments in the therapies of the "more than natural." And then, finally, we can offer a present view of the implants, transplants, and other parts of the medicine of the future.

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Mesh:

Year:  1990        PMID: 2221504     DOI: 10.1007/bf02364153

Source DB:  PubMed          Journal:  Ann Biomed Eng        ISSN: 0090-6964            Impact factor:   3.934


  6 in total

1.  The Molecule of the Year.

Authors:  R L Guyer; D E Koshland
Journal:  Science       Date:  1989-12-22       Impact factor: 47.728

2.  Researchers follow varied molecular paths toward better control of organ rejection.

Authors:  M F Goldsmith
Journal:  JAMA       Date:  1990-03-02       Impact factor: 56.272

3.  Recombinant gene expression in vivo within endothelial cells of the arterial wall.

Authors:  E G Nabel; G Plautz; F M Boyce; J C Stanley; G J Nabel
Journal:  Science       Date:  1989-06-16       Impact factor: 47.728

4.  Implantation of vascular grafts lined with genetically modified endothelial cells.

Authors:  J M Wilson; L K Birinyi; R N Salomon; P Libby; A D Callow; R C Mulligan
Journal:  Science       Date:  1989-06-16       Impact factor: 47.728

5.  Heparin-binding growth factor 1 induces the formation of organoid neovascular structures in vivo.

Authors:  J A Thompson; C C Haudenschild; K D Anderson; J M DiPietro; W F Anderson; T Maciag
Journal:  Proc Natl Acad Sci U S A       Date:  1989-10       Impact factor: 11.205

6.  Seeding of intravascular stents with genetically engineered endothelial cells.

Authors:  D A Dichek; R F Neville; J A Zwiebel; S M Freeman; M B Leon; W F Anderson
Journal:  Circulation       Date:  1989-11       Impact factor: 29.690

  6 in total

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