Literature DB >> 22214455

The chlorophyll catabolite pheophorbide a as a photosensitizer for the photodynamic therapy.

L E Xodo1, V Rapozzi, M Zacchigna, S Drioli, S Zorzet.   

Abstract

Pheophorbide a is a clorophyll catabolite that recently has drawn the attention of several investigators for its potential in photodynamic therapy. In this review we summarize its photophysical properties, phototoxicity, cellular localization, biodistribution and PDT activity as a free or conjugated molecule.

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Year:  2012        PMID: 22214455     DOI: 10.2174/092986712799034879

Source DB:  PubMed          Journal:  Curr Med Chem        ISSN: 0929-8673            Impact factor:   4.530


  18 in total

1.  The PDT activity of free and pegylated pheophorbide a against an amelanotic melanoma transplanted in C57/BL6 mice.

Authors:  Valentina Rapozzi; Sonia Zorzet; Marina Zacchigna; Sara Drioli; Luigi E Xodo
Journal:  Invest New Drugs       Date:  2012-06-12       Impact factor: 3.850

2.  RUNX3 confers sensitivity to pheophorbide a-photodynamic therapy in human oral squamous cell carcinoma cell lines.

Authors:  Sook Moon; Jung Yoon Bae; Hwa-Kyung Son; Doo Young Lee; Gyeongju Park; Hyun You; Hyojin Ko; Yong-Chul Kim; Jin Kim
Journal:  Lasers Med Sci       Date:  2013-05-23       Impact factor: 3.161

3.  A Role for TIC55 as a Hydroxylase of Phyllobilins, the Products of Chlorophyll Breakdown during Plant Senescence.

Authors:  Mareike Hauenstein; Bastien Christ; Aditi Das; Sylvain Aubry; Stefan Hörtensteiner
Journal:  Plant Cell       Date:  2016-09-21       Impact factor: 11.277

4.  Chlorophyll-related compounds inhibit cell adhesion and inflammation in human aortic cells.

Authors:  Kuan-Hung Lin; Ching-Yun Hsu; Ya-Ping Huang; Jun-You Lai; Wen-Bin Hsieh; Meng-Yuan Huang; Chi-Ming Yang; Pi-Yu Chao
Journal:  J Med Food       Date:  2013-09-25       Impact factor: 2.786

5.  Magnetic chitosan/graphene oxide composite loaded with novel photosensitizer for enhanced photodynamic therapy.

Authors:  Xiang Qin; Hongyue Zhang; Zhiqiang Wang; Yingxue Jin
Journal:  RSC Adv       Date:  2018-03-14       Impact factor: 4.036

6.  Anticancer activity of cationic porphyrins in melanoma tumour-bearing mice and mechanistic in vitro studies.

Authors:  Valentina Rapozzi; Sonia Zorzet; Marina Zacchigna; Emilia Della Pietra; Susanna Cogoi; Luigi E Xodo
Journal:  Mol Cancer       Date:  2014-04-01       Impact factor: 27.401

7.  Nanoencapsulation of the sasanquasaponin from Camellia oleifera, its photo responsiveness and neuroprotective effects.

Authors:  Yong Ye; Haiting Xing; Yue Li
Journal:  Int J Nanomedicine       Date:  2014-09-19

8.  Photoresponsive nanocapsulation of cobra neurotoxin and enhancement of its central analgesic effects under red light.

Authors:  Qian Yang; Chuang Zhao; Jun Zhao; Yong Ye
Journal:  Int J Nanomedicine       Date:  2017-05-02

9.  Photodynamic Synergistic Effect of Pheophorbide a and Doxorubicin in Combined Treatment against Tumoral Cells.

Authors:  Rubén Ruiz-González; Paula Milán; Roger Bresolí-Obach; Juan Carlos Stockert; Angeles Villanueva; Magdalena Cañete; Santi Nonell
Journal:  Cancers (Basel)       Date:  2017-02-17       Impact factor: 6.639

10.  The sensitivity of cancer cells to pheophorbide a-based photodynamic therapy is enhanced by Nrf2 silencing.

Authors:  Bo-hyun Choi; In-geun Ryoo; Han Chang Kang; Mi-Kyoung Kwak
Journal:  PLoS One       Date:  2014-09-16       Impact factor: 3.240

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