Literature DB >> 22213274

Bending the prescription opioid dosing and mortality curves: impact of the Washington State opioid dosing guideline.

Gary M Franklin1, Jaymie Mai, Judith Turner, Mark Sullivan, Thomas Wickizer, Deborah Fulton-Kehoe.   

Abstract

BACKGROUND: Opioid use and dosing for patients with chronic non-cancer pain have dramatically increased over the past decade, resulting in a national epidemic of mortality associated with unintentional overdose, and increased risk of disability among injured workers. We assessed changes in opioid dosing patterns and opioid-related mortality in the Washington State (WA) workers' compensation system following implementation of a specific WA opioid dosing guideline in April, 2007.
METHODS: Using detailed computerized billing data from WA workers' compensation, we report overall prevalence of opioid prescriptions, average morphine-equivalent dose (MED)/day, and proportion of workers on disability compensation receiving opioids and high-dose (≥120 mg/day MED) opioids over the past decade. We also report the trend of unintentional opioid deaths during the same time period.
RESULTS: Compared to before 2007, there has been a substantial decline in both the MED/day of long-acting DEA Schedule II opioids (by 27%) and the proportion of workers on doses ≥120 md/day MED (by 35%). There was a 50% decrease from 2009 to 2010 in the number of deaths.
CONCLUSIONS: The introduction in WA of an opioid dosing guideline appears to be associated temporally with a decline in the mean dose for long-acting opioids, percent of claimants receiving opioid doses ≥120 mg MED per day, and number of opioid-related deaths among injured workers.
Copyright © 2011 Wiley Periodicals, Inc.

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Year:  2011        PMID: 22213274     DOI: 10.1002/ajim.21998

Source DB:  PubMed          Journal:  Am J Ind Med        ISSN: 0271-3586            Impact factor:   2.214


  55 in total

1.  Anxiety, depression, and opioid misuse among adults with chronic pain: the role of emotion dysregulation.

Authors:  Andrew H Rogers; Michael F Orr; Justin M Shepherd; Jafar Bakhshaie; Joseph W Ditre; Julia D Buckner; Michael J Zvolensky
Journal:  J Behav Med       Date:  2020-06-27

2.  Opioid Overdose Hospitalization Trajectories in States With and Without Opioid-Dosing Guidelines.

Authors:  Jeanne M Sears; Deborah Fulton-Kehoe; Beryl A Schulman; Sheilah Hogg-Johnson; Gary M Franklin
Journal:  Public Health Rep       Date:  2019-07-31       Impact factor: 2.792

3.  Overdoses in Patients on Opioids: Risks Associated with Mental Health Conditions and Their Treatment.

Authors:  Matthew J Bair; Amy S Bohnert
Journal:  J Gen Intern Med       Date:  2015-08       Impact factor: 5.128

Review 4.  What we know, and don't know, about the impact of state policy and systems-level interventions on prescription drug overdose.

Authors:  Tamara M Haegerich; Leonard J Paulozzi; Brian J Manns; Christopher M Jones
Journal:  Drug Alcohol Depend       Date:  2014-10-14       Impact factor: 4.492

5.  Effective Canadian policy to reduce harms from prescription opioids: learning from past failures.

Authors:  Benedikt Fischer; Jürgen Rehm; Mark Tyndall
Journal:  CMAJ       Date:  2016-11-07       Impact factor: 8.262

Review 6.  Opioids for low back pain.

Authors:  Richard A Deyo; Michael Von Korff; David Duhrkoop
Journal:  BMJ       Date:  2015-01-05

7.  Suicide in the US Army.

Authors:  Timothy W Lineberry; Stephen S O'Connor
Journal:  Mayo Clin Proc       Date:  2012-09       Impact factor: 7.616

8.  The Impact of Opioid Risk Reduction Initiatives on High-Dose Opioid Prescribing for Patients on Chronic Opioid Therapy.

Authors:  Michael Von Korff; Sascha Dublin; Rod L Walker; Michael Parchman; Susan M Shortreed; Ryan N Hansen; Kathleen Saunders
Journal:  J Pain       Date:  2015-10-22       Impact factor: 5.820

Review 9.  Determinants of increased opioid-related mortality in the United States and Canada, 1990-2013: a systematic review.

Authors:  Nicholas B King; Veronique Fraser; Constantina Boikos; Robin Richardson; Sam Harper
Journal:  Am J Public Health       Date:  2014-06-12       Impact factor: 9.308

10.  Preferences for Aftercare Among Persons Seeking Short-Term Opioid Detoxification.

Authors:  Michael D Stein; Bradley J Anderson; Genie L Bailey
Journal:  J Subst Abuse Treat       Date:  2015-07-14
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