Literature DB >> 22212683

Retrospective clinical and laboratory evaluation of children with brucellosis.

Mesut Okur1, Fatih Erbey, Mehmet Selçuk Bektaş, Avni Kaya, Murat Doğan, Mehmet Nuri Acar, Hakan Uzun.   

Abstract

BACKGROUND: Acute brucellosis is a zoonotic disease seen in childhood, with non-specific complaints and clinical findings that can affect the locomotor, gastrointestinal, genitourinary, hematologic, cardiovascular, respiratory, and central nervous systems. Particularly in endemic regions, it occurs as a result of consumption of unpasteurized milk and dairy products. In this study, clinical and laboratory findings of children with acute brucellosis are presented.
METHODS: Data for 147 patients, aged 2-16 years, were evaluated retrospectively.
RESULTS: The most frequent complaints and clinical findings were abdominal pain and fever. Other complaints and clinical findings included arthralgia, myalgia, loss of appetite, weakness, sweating, fatigue, headache, arthritis, hepatomegaly, and splenomegaly. Anemia was the most frequent hematological abnormality detected; other abnormalities included leukopenia, thrombocytopenia, and pancytopenia.
CONCLUSION: Childhood brucellosis can cause non-specific complaints and particularly anemia and leukopenia as hematological abnormalities. It is easily treated, however, with appropriate antibiotics.
© 2011 The Authors. Pediatrics International © 2011 Japan Pediatric Society.

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Year:  2012        PMID: 22212683     DOI: 10.1111/j.1442-200X.2011.03558.x

Source DB:  PubMed          Journal:  Pediatr Int        ISSN: 1328-8067            Impact factor:   1.524


  5 in total

1.  A prospective study of brucellosis in children: relative frequency of pancytopenia.

Authors:  Mohamad A El-Koumi; Mona Afify; Salha H Al-Zahrani
Journal:  Iran J Pediatr       Date:  2014-04       Impact factor: 0.364

2.  A human stool-derived Bilophila wadsworthia strain caused systemic inflammation in specific-pathogen-free mice.

Authors:  Zhou Feng; Wenmin Long; Binhan Hao; Ding Ding; Xiaoqing Ma; Liping Zhao; Xiaoyan Pang
Journal:  Gut Pathog       Date:  2017-10-26       Impact factor: 4.181

3.  Epidemiological, Risk Factors, Clinical, and Laboratory Features of Brucellosis in the Southwest of Iran within 2009-2015.

Authors:  Mahmood Nabavi; Hossein Hatami; Hedayatollah Jamaliarand
Journal:  Int J Prev Med       Date:  2019-06-12

4.  A prospective study of brucellosis in children: relative frequency of pancytopenia.

Authors:  Mohamed A El-Koumi; Mona Afify; Salha H Al-Zahrani
Journal:  Mediterr J Hematol Infect Dis       Date:  2013-02-16       Impact factor: 2.576

Review 5.  Pediatric brucellosis. An update review for the new millennium.

Authors:  Elham E Bukhari
Journal:  Saudi Med J       Date:  2018-04       Impact factor: 1.484

  5 in total

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