Literature DB >> 22212598

Ketamine effects on brain GABA and glutamate levels with 1H-MRS: relationship to ketamine-induced psychopathology.

J M Stone, C Dietrich, R Edden, M A Mehta, S De Simoni, L J Reed, J H Krystal, D Nutt, G J Barker.   

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Year:  2012        PMID： 22212598      PMCID： PMC3883303          DOI： 10.1038/mp.2011.171

Source DB:  PubMed          Journal:  Mol Psychiatry        ISSN： 1359-4184            Impact factor:   15.992


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  10 in total

1.  Effects of ketamine on anterior cingulate glutamate metabolism in healthy humans: a 4-T proton MRS study.

Authors:  Laura M Rowland; Juan R Bustillo; Paul G Mullins; Rex E Jung; Rhoshel Lenroot; Elma Landgraf; Ranee Barrow; Ronald Yeo; John Lauriello; William M Brooks
Journal:  Am J Psychiatry       Date:  2005-02       Impact factor: 18.112

2.  NMDA receptor hypofunction produces opposite effects on prefrontal cortex interneurons and pyramidal neurons.

Authors:  Houman Homayoun; Bita Moghaddam
Journal:  J Neurosci       Date:  2007-10-24       Impact factor: 6.167

3.  Glutamate and glutamine measured with 4.0 T proton MRS in never-treated patients with schizophrenia and healthy volunteers.

Authors:  Jean Théberge; Robert Bartha; Dick J Drost; Ravi S Menon; Ashok Malla; Jatinder Takhar; Richard W Neufeld; John Rogers; William Pavlosky; Betsy Schaefer; Maria Densmore; Yousef Al-Semaan; Peter C Williamson
Journal:  Am J Psychiatry       Date:  2002-11       Impact factor: 18.112

Review 4.  Region and state specific glutamate downregulation in major depressive disorder: a meta-analysis of (1)H-MRS findings.

Authors:  J J Luykx; K G Laban; M P van den Heuvel; M P M Boks; R C W Mandl; R S Kahn; S C Bakker
Journal:  Neurosci Biobehav Rev       Date:  2011-06-06       Impact factor: 8.989

5.  In vivo and ex vivo evidence for ketamine-induced hyperglutamatergic activity in the cerebral cortex of the rat: Potential relevance to schizophrenia.

Authors:  Sang-Young Kim; Hyunseung Lee; Hyun-Ju Kim; Eunjung Bang; Sung-Ho Lee; Do-Wan Lee; Dong-Cheol Woo; Chi-Bong Choi; Kwan Soo Hong; Chulhyun Lee; Bo-Young Choe
Journal:  NMR Biomed       Date:  2011-05-11       Impact factor: 4.044

6.  The antidepressant effect of ketamine is not associated with changes in occipital amino acid neurotransmitter content as measured by [(1)H]-MRS.

Authors:  Gerald W Valentine; Graeme F Mason; Rosane Gomez; Madonna Fasula; June Watzl; Brian Pittman; John H Krystal; Gerard Sanacora
Journal:  Psychiatry Res       Date:  2011-01-12       Impact factor: 3.222

7.  Activation of glutamatergic neurotransmission by ketamine: a novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex.

Authors:  B Moghaddam; B Adams; A Verma; D Daly
Journal:  J Neurosci       Date:  1997-04-15       Impact factor: 6.167

8.  Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.

Authors:  J H Krystal; L P Karper; J P Seibyl; G K Freeman; R Delaney; J D Bremner; G R Heninger; M B Bowers; D S Charney
Journal:  Arch Gen Psychiatry       Date:  1994-03

9.  Glutamate dysfunction in people with prodromal symptoms of psychosis: relationship to gray matter volume.

Authors:  James M Stone; Fern Day; Helen Tsagaraki; Isabel Valli; Mary A McLean; David J Lythgoe; Ruth L O'Gorman; Gareth J Barker; Philip K McGuire
Journal:  Biol Psychiatry       Date:  2009-06-25       Impact factor: 13.382

10.  Muscimol prevents NMDA antagonist neurotoxicity by activating GABAA receptors in several brain regions.

Authors:  Nuri B Farber; Xiaoping Jiang; Krikor Dikranian; Brian Nemmers
Journal:  Brain Res       Date:  2003-12-12       Impact factor: 3.252
  10 in total
  119 in total

1.  Phenomenologically distinct psychotomimetic effects of ketamine are associated with cerebral blood flow changes in functionally relevant cerebral foci: a continuous arterial spin labelling study.

Authors:  T A Pollak; S De Simoni; B Barimani; F O Zelaya; J M Stone; M A Mehta
Journal:  Psychopharmacology (Berl)       Date:  2015-10-05       Impact factor: 4.530

2.  Increasing doses of ketamine curtail antidepressant responses and suppress associated synaptic signaling pathways.

Authors:  Ji-Woon Kim; Lisa M Monteggia
Journal:  Behav Brain Res       Date:  2019-11-21       Impact factor: 3.332

3.  In vivo ketamine-induced changes in [¹¹C]ABP688 binding to metabotropic glutamate receptor subtype 5.

Authors:  Christine DeLorenzo; Nicole DellaGioia; Michael Bloch; Gerard Sanacora; Nabeel Nabulsi; Chadi Abdallah; Jie Yang; Ruofeng Wen; J John Mann; John H Krystal; Ramin V Parsey; Richard E Carson; Irina Esterlis
Journal:  Biol Psychiatry       Date:  2014-07-10       Impact factor: 13.382

Review 4.  Glutamate-mediated excitotoxicity in schizophrenia: a review.

Authors:  Eric Plitman; Shinichiro Nakajima; Camilo de la Fuente-Sandoval; Philip Gerretsen; M Mallar Chakravarty; Jane Kobylianskii; Jun Ku Chung; Fernando Caravaggio; Yusuke Iwata; Gary Remington; Ariel Graff-Guerrero
Journal:  Eur Neuropsychopharmacol       Date:  2014-08-01       Impact factor: 4.600

5.  Timosaponin derivative YY-23 acts as a non-competitive NMDA receptor antagonist and exerts a rapid antidepressant-like effect in mice.

Authors:  Qi Zhang; Fei Guo; Zhi-wen Fu; Bing Zhang; Cheng-gang Huang; Yang Li
Journal:  Acta Pharmacol Sin       Date:  2015-12-21       Impact factor: 6.150

Review 6.  Impaired Tuning of Neural Ensembles and the Pathophysiology of Schizophrenia: A Translational and Computational Neuroscience Perspective.

Authors:  John H Krystal; Alan Anticevic; Genevieve J Yang; George Dragoi; Naomi R Driesen; Xiao-Jing Wang; John D Murray
Journal:  Biol Psychiatry       Date:  2017-01-13       Impact factor: 13.382

7.  Ketamine induced changes in regional cerebral blood flow, interregional connectivity patterns, and glutamate metabolism.

Authors:  James Edward Bryant; Michael Frölich; Steve Tran; Meredith Amanda Reid; Adrienne Carol Lahti; Nina Vanessa Kraguljac
Journal:  J Psychiatr Res       Date:  2019-07-27       Impact factor: 4.791

8.  Imaging patients with psychosis and a mouse model establishes a spreading pattern of hippocampal dysfunction and implicates glutamate as a driver.

Authors:  Scott A Schobel; Nashid H Chaudhury; Usman A Khan; Beatriz Paniagua; Martin A Styner; Iris Asllani; Benjamin P Inbar; Cheryl M Corcoran; Jeffrey A Lieberman; Holly Moore; Scott A Small
Journal:  Neuron       Date:  2013-04-10       Impact factor: 17.173

9.  Default mode network connectivity change corresponds to ketamine's delayed glutamatergic effects.

Authors:  Meng Li; Marie Woelfer; Lejla Colic; Adam Safron; Catie Chang; Hans-Jochen Heinze; Oliver Speck; Helen S Mayberg; Bharat B Biswal; Giacomo Salvadore; Anna Fejtova; Martin Walter
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2018-10-23       Impact factor: 5.270

10.  Effects of ketamine on brain function during response inhibition.

Authors:  M Steffens; C Neumann; A-M Kasparbauer; B Becker; B Weber; M A Mehta; R Hurlemann; U Ettinger
Journal:  Psychopharmacology (Berl)       Date:  2018-10-24       Impact factor: 4.530
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