Literature DB >> 22211976

Systems biology of the heart: hype or hope?

T Alexander Quinn1, Peter Kohl.   

Abstract

Systems biology, the approach that combines reduction and integration to explore dynamic structure-function interrelations across biomedically relevant spatio-temporal scales, is applied to heart research.
© 2011 New York Academy of Sciences.

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Year:  2011        PMID： 22211976     DOI： 10.1111/j.1749-6632.2011.06327.x

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN： 0077-8923            Impact factor:   5.691


  13 in total

Review 1.  What keeps us ticking? Sinoatrial node mechano-sensitivity: the grandfather clock of cardiac rhythm.

Authors:  Eilidh A MacDonald; T Alexander Quinn
Journal:  Biophys Rev       Date:  2021-09-15

2.  A vision and strategy for the virtual physiological human: 2012 update.

Authors:  Peter Hunter; Tara Chapman; Peter V Coveney; Bernard de Bono; Vanessa Diaz; John Fenner; Alejandro F Frangi; Peter Harris; Rod Hose; Peter Kohl; Pat Lawford; Keith McCormack; Miriam Mendes; Stig Omholt; Alfio Quarteroni; Nour Shublaq; John Skår; Karl Stroetmann; Jesper Tegner; S Randall Thomas; Ioannis Tollis; Ioannis Tsamardinos; Johannes H G M van Beek; Marco Viceconti
Journal:  Interface Focus       Date:  2013-04-06       Impact factor: 3.906

Review 3.  The importance of non-uniformities in mechano-electric coupling for ventricular arrhythmias.

Authors:  T Alexander Quinn
Journal:  J Interv Card Electrophysiol       Date:  2013-12-12       Impact factor: 1.900

Review 4.  Fibroblast-myocyte electrotonic coupling: does it occur in native cardiac tissue?

Authors:  Peter Kohl; Robert G Gourdie
Journal:  J Mol Cell Cardiol       Date:  2014-01-08       Impact factor: 5.000

Review 5.  Altered Calcium Handling and Ventricular Arrhythmias in Acute Ischemia.

Authors:  Peter Baumeister; T Alexander Quinn
Journal:  Clin Med Insights Cardiol       Date:  2016-12-14

Review 6.  Mechano-sensitivity of cardiac pacemaker function: pathophysiological relevance, experimental implications, and conceptual integration with other mechanisms of rhythmicity.

Authors:  T Alexander Quinn; Peter Kohl
Journal:  Prog Biophys Mol Biol       Date:  2012-08-21       Impact factor: 3.667

Review 7.  Combining wet and dry research: experience with model development for cardiac mechano-electric structure-function studies.

Authors:  T Alexander Quinn; Peter Kohl
Journal:  Cardiovasc Res       Date:  2013-01-17       Impact factor: 10.787

8.  Population of computational rabbit-specific ventricular action potential models for investigating sources of variability in cellular repolarisation.

Authors:  Philip Gemmell; Kevin Burrage; Blanca Rodriguez; T Alexander Quinn
Journal:  PLoS One       Date:  2014-02-28       Impact factor: 3.240

9.  Variability in cardiac electrophysiology: Using experimentally-calibrated populations of models to move beyond the single virtual physiological human paradigm.

Authors:  Anna Muszkiewicz; Oliver J Britton; Philip Gemmell; Elisa Passini; Carlos Sánchez; Xin Zhou; Annamaria Carusi; T Alexander Quinn; Kevin Burrage; Alfonso Bueno-Orovio; Blanca Rodriguez
Journal:  Prog Biophys Mol Biol       Date:  2015-12-14       Impact factor: 3.667

Review 10.  Rabbit models of cardiac mechano-electric and mechano-mechanical coupling.

Authors:  T Alexander Quinn; Peter Kohl
Journal:  Prog Biophys Mol Biol       Date:  2016-05-18       Impact factor: 3.667
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