Literature DB >> 22211966

Novel, nonreflex tests detect analgesic action in rodents at clinically relevant concentrations.

Nick Andrews1, Sinead Harper, Yasmin Issop, Andrew S C Rice.   

Abstract

We propose that predictive validity of tests for analgesia may be improved by looking to reinstate specific, innate behaviors suppressed by pain, e.g., burrowing, because effective plasma concentrations in the rat are closer to effective clinical plasma concentrations than those generally used in rodent reflex withdrawal assays.
© 2011 New York Academy of Sciences.

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Year:  2011        PMID： 22211966     DOI： 10.1111/j.1749-6632.2011.06342.x

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN： 0077-8923            Impact factor:   5.691


  11 in total

Review 1.  A critical evaluation of validity and utility of translational imaging in pain and analgesia: Utilizing functional imaging to enhance the process.

Authors:  Jaymin Upadhyay; Christian Geber; Richard Hargreaves; Frank Birklein; David Borsook
Journal:  Neurosci Biobehav Rev       Date:  2017-08-12       Impact factor: 8.989

Review 2.  Pros and Cons of Clinically Relevant Methods to Assess Pain in Rodents.

Authors:  Anke Tappe-Theodor; Tamara King; Michael M Morgan
Journal:  Neurosci Biobehav Rev       Date:  2019-03-15       Impact factor: 8.989

Review 3.  Lost but making progress--Where will new analgesic drugs come from?

Authors:  David Borsook; Richard Hargreaves; Chas Bountra; Frank Porreca
Journal:  Sci Transl Med       Date:  2014-08-13       Impact factor: 17.956

4.  Cancer-induced Bone Pain Impairs Burrowing Behaviour in Mouse and Rat.

Authors:  Sonny Hermanus Johannes Sliepen; Marta Diaz-Delcastillo; Johanna Korioth; Rikke Brix Olsen; Camilla Kristine Appel; Thomas Christoph; Anne-Marie Heegaard; Kris Rutten
Journal:  In Vivo       Date:  2019 Jul-Aug       Impact factor: 2.155

Review 5.  Improving the translation of analgesic drugs to the clinic: animal models of neuropathic pain.

Authors:  N Percie du Sert; A S C Rice
Journal:  Br J Pharmacol       Date:  2014-06       Impact factor: 8.739

6.  Effects of the triple monoamine uptake inhibitor amitifadine on pain-related depression of behavior and mesolimbic dopamine release in rats.

Authors:  Laurence L Miller; Michael D Leitl; Matthew L Banks; Bruce E Blough; S Stevens Negus
Journal:  Pain       Date:  2015-01       Impact factor: 7.926

Review 7.  The search for novel analgesics: targets and mechanisms.

Authors:  Tony L Yaksh; Sarah A Woller; Roshni Ramachandran; Linda S Sorkin
Journal:  F1000Prime Rep       Date:  2015-05-26

8.  Comparison of Burrowing and Stimuli-Evoked Pain Behaviors as End-Points in Rat Models of Inflammatory Pain and Peripheral Neuropathic Pain.

Authors:  Arjun Muralidharan; Andy Kuo; Meera Jacob; Jacintha S Lourdesamy; Lara Melo Soares Pinho De Carvalho; Janet R Nicholson; Laura Corradini; Maree T Smith
Journal:  Front Behav Neurosci       Date:  2016-05-10       Impact factor: 3.558

9.  Evoked and Ongoing Pain-Like Behaviours in a Rat Model of Paclitaxel-Induced Peripheral Neuropathy.

Authors:  Lisa A Griffiths; Natalie A Duggett; Ann L Pitcher; Sarah J L Flatters
Journal:  Pain Res Manag       Date:  2018-06-03       Impact factor: 3.037

10.  An Electroencephalography Bioassay for Preclinical Testing of Analgesic Efficacy.

Authors:  Suguru Koyama; Brian W LeBlanc; Kelsey A Smith; Catherine Roach; Joshua Levitt; Muhammad M Edhi; Mai Michishita; Takayuki Komatsu; Okishi Mashita; Aki Tanikawa; Satoru Yoshikawa; Carl Y Saab
Journal:  Sci Rep       Date:  2018-11-06       Impact factor: 4.379
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