Literature DB >> 22210482

Willingness of clinicians to integrate microbicides into HIV prevention practices in southern Africa.

Cynthia C Harper1, Kelsey Holt, Taazadza Nhemachena, Tsungai Chipato, Gita Ramjee, Laura Stratton, Maya Blum, Charles E McCulloch, Sibongile Mgweba, Kelly Blanchard.   

Abstract

The first vaginal microbicide was recently proven effective in clinical trials. We assessed the willingness of clinicians to integrate microbicides into HIV prevention practices in Southern Africa, where women face elevated HIV risks. We conducted in-depth interviews (n = 60) and nationally representative surveys (n = 1,444) in South Africa and Zimbabwe with nurses and physicians. Over half of clinicians (58%) were aware of microbicides, with physicians far more likely than nurses to be familiar. Clinicians, including those in rural areas, were generally willing to discuss microbicides, a female-initiated method less effective than the condom, particularly when condom use was unlikely (70%). Fewer would include microbicides while counseling adolescents (51%). Most clinicians (85%) thought their patients would use microbicides; greater clinician familiarity with microbicides was significant for support. Training for both nurses and physicians prior to introduction is critical, so they have sufficient knowledge and skills to offer a microbicide upon availability.

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Year:  2012        PMID: 22210482      PMCID: PMC3745300          DOI: 10.1007/s10461-011-0109-6

Source DB:  PubMed          Journal:  AIDS Behav        ISSN: 1090-7165


  24 in total

1.  Disseminating innovations in health care.

Authors:  Donald M Berwick
Journal:  JAMA       Date:  2003-04-16       Impact factor: 56.272

2.  The female condom: the international denial of a strong potential.

Authors:  Anny Peters; Willy Jansen; Francien van Driel
Journal:  Reprod Health Matters       Date:  2010-05

3.  Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women.

Authors:  Quarraisha Abdool Karim; Salim S Abdool Karim; Janet A Frohlich; Anneke C Grobler; Cheryl Baxter; Leila E Mansoor; Ayesha B M Kharsany; Sengeziwe Sibeko; Koleka P Mlisana; Zaheen Omar; Tanuja N Gengiah; Silvia Maarschalk; Natasha Arulappan; Mukelisiwe Mlotshwa; Lynn Morris; Douglas Taylor
Journal:  Science       Date:  2010-07-19       Impact factor: 47.728

4.  Efficacy of Carraguard for prevention of HIV infection in women in South Africa: a randomised, double-blind, placebo-controlled trial.

Authors:  Stephanie Skoler-Karpoff; Gita Ramjee; Khatija Ahmed; Lydia Altini; Marlena Gehret Plagianos; Barbara Friedland; Sumen Govender; Alana De Kock; Nazira Cassim; Thesla Palanee; Gregory Dozier; Robin Maguire; Pekka Lahteenmaki
Journal:  Lancet       Date:  2008-12-06       Impact factor: 79.321

5.  Physicians' beliefs about conscience in medicine: a national survey.

Authors:  Ryan E Lawrence; Farr A Curlin
Journal:  Acad Med       Date:  2009-09       Impact factor: 6.893

6.  Condom use within marital and cohabiting partnerships in KwaZulu-Natal, South Africa.

Authors:  Pranitha Maharaj; John Cleland
Journal:  Stud Fam Plann       Date:  2004-06

7.  Consistent condom use in married Zimbabwean women after a condom intervention.

Authors:  Lisa Callegari; Cynthia C Harper; Ariane van der Straten; Mavis Kamba; Tsungai Chipato; Nancy S Padian
Journal:  Sex Transm Dis       Date:  2008-06       Impact factor: 2.830

Review 8.  Shifts in condom use following microbicide introduction: should we be concerned?

Authors:  Anna M Foss; Peter T Vickerman; Lori Heise; Charlotte H Watts
Journal:  AIDS       Date:  2003-05-23       Impact factor: 4.177

9.  Sexuality, HIV risk and potential acceptability of involving adolescent girls in microbicide research in Kisumu, Kenya.

Authors:  Michele Montandon; Nuriye Nalan Sahin-Hodoglugil; Elizabeth Bukusi; Kawango Agot; Brigid Boland; Craig R Cohen
Journal:  Sex Health       Date:  2008-12       Impact factor: 2.706

10.  Household and community income, economic shocks and risky sexual behavior of young adults: evidence from the Cape Area Panel Study 2002 and 2005.

Authors:  Taryn Dinkelman; David Lam; Murray Leibbrandt
Journal:  AIDS       Date:  2007-11       Impact factor: 4.177

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  4 in total

1.  Clinicians' perceptions and provision of hormonal contraceptives for HIV-positive and at-risk women in Southern Africa: an original research article.

Authors:  Kelly Blanchard; Tsungai Chipato; Gita Ramjee; Tzadzaa Nhemachena; Cynthia C Harper
Journal:  Contraception       Date:  2014-05-04       Impact factor: 3.375

2.  Provision of long-acting reversible contraception in HIV-prevalent countries: results from nationally representative surveys in southern Africa.

Authors:  J Morse; T Chipato; K Blanchard; T Nhemachena; G Ramjee; C McCulloch; M Blum; E Saleeby; C C Harper
Journal:  BJOG       Date:  2013-05-31       Impact factor: 6.531

3.  A nationally representative survey of healthcare provider counselling and provision of the female condom in South Africa and Zimbabwe.

Authors:  Kelsey Holt; Kelly Blanchard; Tsungai Chipato; Taazadza Nhemachena; Maya Blum; Laura Stratton; Neetha Morar; Gita Ramjee; Cynthia C Harper
Journal:  BMJ Open       Date:  2013-03-18       Impact factor: 2.692

Review 4.  Nanoparticles as potential new generation broad spectrum antimicrobial agents.

Authors:  Clarence S Yah; Geoffrey S Simate
Journal:  Daru       Date:  2015-09-02       Impact factor: 3.117

  4 in total

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