OBJECTIVES: To clarify whether interleukin (IL)-23 is involved in peripheral arterial disease (PAD). DESIGN AND METHODS: We evaluated IL-23 serum levels, in 29 patients suffering from lower extremity PAD and in 30 healthy subjects. RESULTS: IL-23 serum levels were higher during the three times (T0, T1 and T2) compared to the control group, although only statistically significant for T0 and T2: T0 (15.83 ± 22.08 vs. 8.08 ± 8.62 pg ml, p=0.026), T1 (16.10 ± 23.71 vs. 8.08 ± 8.62 pg/ml, p=0.101), T2 (15.06 ± 16.72 vs. 8.08 ± 8.62 pg/ml, p=0.005). CONCLUSION: For the first time, our data gives us reason to believe there is an involvement of IL-23 in PAD.
OBJECTIVES: To clarify whether interleukin (IL)-23 is involved in peripheral arterial disease (PAD). DESIGN AND METHODS: We evaluated IL-23 serum levels, in 29 patients suffering from lower extremity PAD and in 30 healthy subjects. RESULTS:IL-23 serum levels were higher during the three times (T0, T1 and T2) compared to the control group, although only statistically significant for T0 and T2: T0 (15.83 ± 22.08 vs. 8.08 ± 8.62 pg ml, p=0.026), T1 (16.10 ± 23.71 vs. 8.08 ± 8.62 pg/ml, p=0.101), T2 (15.06 ± 16.72 vs. 8.08 ± 8.62 pg/ml, p=0.005). CONCLUSION: For the first time, our data gives us reason to believe there is an involvement of IL-23 in PAD.
Authors: Cian P McCarthy; Nasrien E Ibrahim; Roland R J van Kimmenade; Hanna K Gaggin; Mandy L Simon; Parul Gandhi; Noreen Kelly; Shweta R Motiwala; Renata Mukai; Craig A Magaret; Grady Barnes; Rhonda F Rhyne; Joseph M Garasic; James L Januzzi Journal: Clin Cardiol Date: 2018-06-14 Impact factor: 2.882
Authors: Giovanni De Caridi; Mafalda Massara; Francesco Spinelli; Antonio David; Sebastiano Gangemi; Francesco Fugetto; Raffaele Grande; Lucia Butrico; Roberta Stefanelli; Manuela Colosimo; Stefano de Franciscis; Raffaele Serra Journal: Int Wound J Date: 2015-05-27 Impact factor: 3.315
Authors: Katarzyna Fischer; Hanna Przepiera-Będzak; Marcin Sawicki; Anna Walecka; Iwona Brzosko; Marek Brzosko Journal: Mediators Inflamm Date: 2017-12-21 Impact factor: 4.711
Authors: Cian P McCarthy; Shreya Shrestha; Nasrien Ibrahim; Roland R J van Kimmenade; Hanna K Gaggin; Renata Mukai; Craig Magaret; Grady Barnes; Rhonda Rhyne; Joseph M Garasic; James L Januzzi Journal: Open Heart Date: 2019-05-13
Authors: Sylwia Wasiak; Dean Gilham; Laura M Tsujikawa; Christopher Halliday; Karen Norek; Reena G Patel; Kevin G McLure; Peter R Young; Allan Gordon; Ewelina Kulikowski; Jan Johansson; Michael Sweeney; Norman C Wong Journal: Data Brief Date: 2016-07-29