Literature DB >> 22209478

[Proposal for a new multidisciplinary therapeutic strategy in the breast cancer patient with sentinel lymph node metastasis].

Benigno Acea1, Lourdes Calvo Martínez, Silvia Antolín Novoa, Luis Albaina Latorre, Manuel Juaneda Magdalena, Paz Santiago Freijanes, Carmen Silva Rodríguez, Joaquín Mosquera Osés, José R Varela Romero, Rafael Soler Fernández, Isabel Facio Villanueva, Isabel Candal Casado, Carmen Cereijo Garea.   

Abstract

Sentinel lymph node (SLN) biopsy is the standard of practice for assessing axillary spread in clinically node-negative breast cancer patients. On the other hand, axillary lymph node dissection (ALND) is the ideal procedure for patients with SLN metastasis. Different studies over the last few years have suggested that some patients with positive SLN can be treated without ALND. This article presents a literature review carried out by our multidisciplinary group and its strategy for avoiding routine ALND in women with SLN metastases. In this new strategy ALND should not be performed on women with T1 tumours, with 1-2 positive SLN and undergoing breast conservative surgery. On the other hand, ALND would be indicated in those patients with three or more positive SLN, presence of extracapsular invasion, mastectomised women and triple negative subtype or HER2+ tumours that have not received biological treatment with antibodies.
Copyright © 2011 AEC. Published by Elsevier Espana. All rights reserved.

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Year:  2011        PMID: 22209478     DOI: 10.1016/j.ciresp.2011.09.004

Source DB:  PubMed          Journal:  Cir Esp        ISSN: 0009-739X            Impact factor:   1.653


  1 in total

Review 1.  Treatment plan for breast cancer with sentinel node metastasis.

Authors:  Efrén Bolívar Abreu; Pedro Martinez; Luis Betancourt; Gabriel Romero; Ali Godoy; Laura Bergamo
Journal:  Ecancermedicalscience       Date:  2014-01-08
  1 in total

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