Literature DB >> 22208907

Ruthenium catalyzed synthesis of enaminones.

Naga Durgarao Koduri1, Halee Scott, Bethany Hileman, Justin D Cox, Michael Coffin, Lindsay Glicksberg, Syed R Hussaini.   

Abstract

The Grubbs first-generation catalyst has been found to be an effective catalyst for the synthesis of enaminones by coupling thioamides with α-diazodicarbonyl compounds. The reaction is successful in converting primary, secondary, and tertiary thioamides into their corresponding enaminones. The reaction is also suitable for the synthesis of chiral enaminones.
© 2011 American Chemical Society

Entities:  

Year:  2011        PMID: 22208907     DOI: 10.1021/ol202812d

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  7 in total

1.  Coupling of acceptor-substituted diazo compounds and tertiary thioamides: synthesis of enamino carbonyl compounds and their pharmacological evaluation.

Authors:  Jim Secka; Arpan Pal; Francis A Acquah; Blaine H M Mooers; Anand B Karki; Dania Mahjoub; Mohamed K Fakhr; David R Wallace; Takuya Okada; Naoki Toyooka; Adama Kuta; Naga Koduri; Deacon Herndon; Kenneth P Roberts; Zhiguo Wang; Bethany Hileman; Nisha Rajagopal; Syed R Hussaini
Journal:  RSC Adv       Date:  2022-07-05       Impact factor: 4.036

2.  Rh(II)-mediated domino [4 + 1]-annulation of α-cyanothioacetamides using diazoesters: A new entry for the synthesis of multisubstituted thiophenes.

Authors:  Jury J Medvedev; Ilya V Efimov; Yuri M Shafran; Vitaliy V Suslonov; Vasiliy A Bakulev; Valerij A Nikolaev
Journal:  Beilstein J Org Chem       Date:  2017-11-30       Impact factor: 2.883

3.  Organocatalytic activation of isocyanides: N-heterocyclic carbene-catalyzed enaminone synthesis from ketones.

Authors:  Jungwon Kim; Soon Hyeok Hong
Journal:  Chem Sci       Date:  2016-12-20       Impact factor: 9.825

4.  Microwave-assisted iodine-catalyzed oxidative coupling of dibenzyl(difurfuryl)disulfides with amines: a rapid and efficient protocol for thioamides.

Authors:  Jinyang Chen; Lan Mei; Jialing Liu; Chuntao Zhong; Binfang Yuan; Qiang Li
Journal:  RSC Adv       Date:  2019-09-10       Impact factor: 4.036

5.  Enantioselective annulations for dihydroquinolones by in situ generation of azolium enolates.

Authors:  Anna Lee; Ashkaan Younai; Christopher K Price; Javier Izquierdo; Rama K Mishra; Karl A Scheidt
Journal:  J Am Chem Soc       Date:  2014-07-15       Impact factor: 15.419

6.  Scale-up of microdroplet reactions by heated ultrasonic nebulization.

Authors:  Chengyuan Liu; Jia Li; Hao Chen; Richard N Zare
Journal:  Chem Sci       Date:  2019-08-19       Impact factor: 9.825

7.  Palladium-catalyzed Suzuki-Miyaura coupling of thioureas or thioamides.

Authors:  Shaoyu Mai; Wendong Li; Xue Li; Yingwei Zhao; Qiuling Song
Journal:  Nat Commun       Date:  2019-12-13       Impact factor: 14.919

  7 in total

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