Literature DB >> 22206463

Rhenium-catalyzed regiodivergent addition of indoles to terminal alkynes.

Dexin Xia1, Yin Wang, Zhenting Du, Qi-Yu Zheng, Congyang Wang.   

Abstract

An efficient rhenium-catalyzed site-switchable addition of indoles to terminal alkynes is described. A variety of bisindolylalkane derivatives are expeditiously synthesized in high yields with excellent regioselectivity. Preliminary mechanistic study sheds light on the observed regiodivergent addition.
© 2011 American Chemical Society

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Year:  2011        PMID： 22206463     DOI： 10.1021/ol203199m

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  2 in total

1.  Metal-free oxidative coupling of arylmethylamines with indoles: a simple, environmentally benign approach for the synthesis of 3,3'-bis(indolyl)methanes.

Authors:  Vikas D Kadu; Sankala Naga Chandrudu; Mahesh G Hublikar; Dattatraya G Raut; Raghunath B Bhosale
Journal:  RSC Adv       Date:  2020-06-17       Impact factor: 4.036

2.  Bis-indolylation of aldehydes and ketones using silica-supported FeCl3: molecular docking studies of bisindoles by targeting SARS-CoV-2 main protease binding sites.

Authors:  Barnali Deb; Sudhan Debnath; Ankita Chakraborty; Swapan Majumdar
Journal:  RSC Adv       Date:  2021-09-16       Impact factor: 4.036
  2 in total

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